I’ve gotten as low as 4.1 but my goal is about 5.0 mg/dL which is reported to be low enough to start dissolving the uric crystals in my joints. Apparently anything above about 5.5 and the uric crystals stay intact. All that said, my uric acid levels can fluctuate significantly on a week to week basis. So, it appears my kidneys “should” be in reasonable condition … I just need to find the right mix that maintains my uric acid level down as low as I want.

Have you tried any fasting?

Interesting about the Losartan; not something I’d heard. I’d opted to not take a prescriptions medication to address my gout when talking to my doctor. I was planning to make the dietary changes needed to lower my uric acid. That has worked … just not as consistent as I’d like.

I didn’t mean to hijack this thread, so I may search to see if there is already a “Gout” thread and/or start another. Thanks for all the feedback so far.

Losartan is the only ARB consistently shown to lower serum uric acid levels.
If your blood pressure is higher than you would like, losartan may be for you for a double benefit. It is widely prescribed by primary physicians and cardiogists.
It has a good safety record and few side effects.

And, of course, you can get it from India.

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A writeup on the scientific paper that Joseph posted earlier:

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I haven’t had any trouble with uric acid levels, so I don’t have a good answer for you. All this being said, I have reduced my niacin dosing per the latest study that shows a link between Niacin and heart disease.

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As I am always willing to try a new supplement that shows promise, I bought some d-Limonene after watching the YouTube video.

This is an almost comical supplement. It does cause weird orange burps. I have been trying it for a few days and find it similar to Acarbose in that the negative effects, in this case, orange-smelling burps, depend on when you take it and what you eat afterward.

As you get old your digestive system seems to be more sensitive to what you eat.
When I was young I had a cast iron stomach and could eat anything. D-Limonene definitely soothes the gut. Hopefully, it has some other benefits mentioned in the YouTube video.
I like it an I think I will take it from now on.

Typical reviews. The positive ones were mainly from people that d-Limonene helped get off of Nexium and Omeprazole. The negative ones were mainly about the orange burping effect and large pill size.

“Taking for digestive/reflux purposes, but has the unintended consequence of making any and all gas from my stomach smell like oranges”

“THESE THINGS WORKED. I stopped taking Omeprazole. I take these once in the morning with coffee and have had ZERO acid reflux. It’s been 2 weeks so far”

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I’ve been supplementing with digestive enzymes for 15 years. Rarely have digestive issues. Theoretically one should get more of the nutrients out of our food as we age and our enzyme activity declines.

This is the one I’ve used most of that time. It does have bromelain in it so people on blood thinners beware.

Webber Naturals Digestive Enzymes

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Wow. I may be interested in trying this. Are there studies on this?

“D-limonene: A multifunctional compound with potent therapeutic effects. (Journal of food biochemistry, 2021)”

“Effect of d-limonene and its derivatives on breast cancer in human trials: a scoping review and narrative synthesis. (BMC cancer, 2021)”

“D-Limonene modulates T lymphocyte activity and viability. (Cellular immunology, 2012)”

“D-Limonene: safety and clinical applications. (Alternative medicine review : a journal of clinical therapeutic, 2007)”

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I found d-limonene to be extremely effective for acid reflux as well.

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Hello, How many mgs and what brand do you take. Thanks. Cheers

Sodium Bicarbonate does the same thing.
Baking Soda (Sodium Bicarbonate) Supplementation to Enhance Training Performance | Dr. Andy Galpin (youtube.com)

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Of course:
I take the Wellness Resources brand from Amazon.
I take one capsule daily in the morning with my coffee.
This is one 1000 mg/capsule.

This is one of the only supplements I take that has an immediate effect.

https://www.amazon.com/Wellness-Resources-d-Limonene-Capsules-1000mg/dp/B0767LR5J9/

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Took it for 2 months- noticed no changes

Are you on a statin?

Guys please avoid any comments on politics. We have a “no politics” policy here. There are lots of other forums for political debate, and we would prefer to keep this one focused on longevity.

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I am sorry, I don’t know what comment on politics you are referring to. I try to avoid commenting on politics and agree that it has no place on this forum.

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I deleted those comments already…

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