#638

It was actually this post that @RapAdmin was referencing. But that was non partisan. However @DrT post wasn’t but he’s Aussie so it’d be like an American talking about vegemite. And yes I’m smarter than vegemite. You have to know that any mention of the names “Trump” or “Biden” (now “Harris”) makes the red light alarm flash in @RapAdmin 's office.

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#639

No. Never have been.

#640

Thanks. I think it only really works as a way to fix the statin problems. I considered trying it even though I’m not on statins either. Think I’ll pass.

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#641

High dose ubiquinol caused me side pain. I’m now only supplementing with low dose ubiqionol once a week which should be sufficient to replenish any inhibited CoQ10.

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#642

A latest video talking about carnosine drop for eye health @LaraPo
The Q is where to get it other than from Russia?

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#643

I can get 99%+ L-Carnosine Powder from one of my suppliers. I’ll get pricing if you are interested. You would have to make your own drops with it though. Should not be difficult at all to make and done right would be reasonably safe.

I’ve made eye drops and nasal sprays, the most important thing, pH and of course sterility.

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#644

Dr Peter Attia - 5 Crucial Supplements Everyone Should Be Taking.

A quick video… Attia seems a bit off his game at the end.

Basically take these 5 supplements:

Magnesium
Creatine
Vitamin B’s
Curcumin
Omega 3

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#645

What happened to vitamin c and taurine?

#646

I think there is evidence for a minimum amount of vitamin C and cycling it up and down.

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#647

For some reason Peter Attia is not fully open about his supplements, lately when asked, he goes by “off the top of my head”.

Whereas someone like him most likely has a spreadsheet, yet never pulls it up…

The most thorough one is when Derek from MPMD went down a fan-made list of Attia’s supplement stack and asked if he was still taking the supplements on that list.

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#648

I think I’ve seen him say that what he is taking (which is driven by blood tests, etc.) should not influence what other people may need to take (which should also be driven by blood test information) - so I could see why he doesn’t share. He knows that people will copy him without doing their own blood tests …

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#649

I now understand that “High-dose spermidine supplementation does not increase spermidine levels in blood plasma and saliva of healthy adults”
I’ll still finish off my bottle of 10mg spermidine supplements but apparently it’s not doing anything. Actually, no, I’m throwing it out. Plenty of other supps these days.

I understand Dr. Michael Greger recommended it but this study doesn’t support it at all so I’ll wait until there’s research suggesting otherwise.

I do also take BPC oral as needed and injection cycles with GHK-cu and TB4. I tried AOD injectable a few times but I just can’t see adequate results even after 8 weeks. Plus it’s a hassle to reconstitute without resulting in gelling, floaters, or cloudiness after a few days or maybe a week with a citrate buffer liquid and BAC.

Also taking K2/D3, creatine, and a coupe of your others. I know it should be taking fewer so looking for some to cut. Tart cherry, mag citrate and a couple others on the cut list.

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#650

Maybe it’s too soon to throw away the spermidine bottle. Its benefits may be derived from the increase in spermine, a similar polyamine, whose concentration is actually elevated after the ingestion of spermidine. The theory needs to be revisited, but the effects still appear to be there.

image

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#651

I try to get spermidine from Shitake mushrooms, which also has a high dose of ergothionine. I look at it like I’m eating mushrooms to get two promising supplements in one. Add the fact that mushrooms have promising anti cancer potential, and it’s a daily staple for me.

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#652

Yes, I looked at his top 5 supplements recently, Attia says he really hates to share, because everyone’s different… their body’s needs are different, nobody understands his clinical context… and if we assume based on his exercise, regiment, diet and lifestyle that we would take the same supplements. His supplements end up online, and then everybody feels that this is what everyone should do for health and he says, it makes no sense.

That said, I did take from him, his use of Carlsons 4 capsules highest amount. Omega Fish Oil… going to add that.

Here’s where he talks about his supplements, and why you shouldn’t copy him.

Link: https://youtube.com/watch?v=TFr3Dmq3uEw&si=YhzjbM1cbfyeHMaS

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#653

Mushrooms constitute a powerful functional food indeed. For those who have not much time to buy and cook them (like myself), there is ample availability of dried mushroom powders and extracts (both solid and liquid).
Probably it is very worthwhile to include one or more supplements derived from mushroom species in the regimen.

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#654

I buy frozen shiitake from the grocery store and microwave a cup of them and eat that way

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#655

Fed this discussion into Claude.ai and asked for a ranking of the supplements discussed based on evidence based studies:

Ranking supplements based on evidence from studies is challenging, as research quality and quantity varies. However, based on the current body of scientific literature, here’s an approximate ranking of the discussed supplements from most to least supported by evidence-based studies:

  1. Vitamin D
  • Extensive research on bone health, immune function, and overall mortality
  1. Omega-3 Fish Oil
  • Strong evidence for cardiovascular benefits and anti-inflammatory effects
  1. Magnesium
  • Well-studied for various health benefits, including cardiovascular and metabolic health
  1. Creatine
  • Robust evidence for improving exercise performance and muscle strength
  1. B Vitamins (as a group)
  • Well-researched for their roles in metabolism and neurological function
  1. Vitamin C
  • Strong evidence for immune function, though benefits of supplementation are debated
  1. Zinc
  • Good evidence for immune function and wound healing
  1. Vitamin K2
  • Growing evidence for bone and cardiovascular health
  1. CoQ10 (Ubiquinol)
  • Good evidence for cardiovascular health, particularly in certain conditions
  1. Selenium
  • Important for thyroid function and antioxidant defense, but benefits of supplementation are mixed
  1. Curcumin
  • Growing body of research on anti-inflammatory effects
  1. Vitamin E
  • Mixed evidence; beneficial in deficiency but potential risks at high doses
  1. Taurine
  • Emerging evidence for cardiovascular and metabolic health
  1. Quercetin
  • Some evidence for anti-inflammatory and antioxidant effects, but more research needed
  1. Resveratrol
  • Promising in lab studies, but human evidence is still limited
  1. Hyaluronic acid
  • Good evidence for joint health and skin benefits when used topically
  1. Spermidine
  • Emerging research, but still limited human studies
  1. L-Carnosine
  • Some evidence for antioxidant effects, but more human studies needed
  1. Beta-carotene
  • Mixed evidence; potentially beneficial from food sources, risks associated with high-dose supplements
  1. Vitamin A
  • Important nutrient, but supplementation has mixed evidence and potential risks
  1. Niacin
  • Benefits for lipid management, but risks at high doses
  1. BPC-157
  • Limited human studies, mostly animal research
  1. GHK-cu
  • Limited human studies, more research needed
  1. Thymosin Beta 4 (TB4)
  • Limited human studies, more research needed
  1. Tauroursodeoxycholic acid
  • Some evidence for liver health, but limited human studies
  1. Ox bile
  • Limited evidence, mainly used for specific digestive issues
  1. Tart cherry
  • Some evidence for exercise recovery and sleep, but more research needed
  1. Ergothioneine
  • Emerging research, but still limited human studies
  1. AOD-9604
  • Limited human studies, more research needed
  1. Mushroom supplements (various)
  • Evidence varies widely depending on the specific type
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#656

I think hemp oil is a better alternative to fish oil… never any risk of mercury plus the omega3 and 6 ratios are the best in hemp oil. Not only that at $12 AUD for 250ml it is an absolute bargain. Too many pluses to ignore.

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#657

Yes, I agree that’s quick, and Shiitake (Lentinus Edodes) is really good-tasting, I too make sure I have fresh mushrooms once a week but beyond that I’m too lazy, so I started to study micotherapy.
Shiitake has many beneficial properties (as the immunomodulatory and anti-carcinogenic function you cite), some shared with other mushrooms and is often used in conjunction with other species.

I realized there are currently only 10-12 species of registered medicinal mushrooms (in Europe), and they are often used in combinations. Some, like the Reishi or Ganoderma Lucidum, are not edible usually; some like the Cordyceps genus are rarely found fresh in the West (never really saw them) or are exceedingly rare and costly (Cordyceps sinensis).

At the end, it is fun to design your own regime of micotherapy, parallel to the regime of conventional supplements and the literature shows so many properties that they are hard to ignore.

At the end I selected 3 species, according to my specific requirements: Ganoderma Lucidum (Reishi), Cordyceps sinensis/militaris and Hericium Erinaceus (Lion’s mane).

My degree of belief in their efficacy is pretty strong (the OP is about ‘thinking’, or ‘believing’, of course after considerate research).

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