#737

Is there a chance that genetic factors might be involved in their longevity?

#738

Is it taurine? Or is it iodine? As you mentioned the people of Japan and Hong Kong eat a diet high in seafood and seaweed. On average they consume much more iodine than in the western diet. Depending on what source you read maybe over 100 times more. Around 13mg per day. The rda in the US is a mere 0.15mg and on average we don’t consume much more than that. Several months ago I started taking Iodoral 12.5mg daily. FWIW, I also take 3gm taurine every day.

https://oawhealth.com/article/iodine-the-universal-nutrient/

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#739

what are the different factors, that drive the high Life Expectancy in some countries? And what causes Low life expectancy in other countries?

General access to high quality health care or not.
Poverty vs wealth? It takes money to fund a good healthcare system.

#740

Looking at the top 10 countries, they’re all located along a sea or ocean except Switzerland. Probably the seafood is a major factor.

Maybe you need to find a place to live on a mountain next to an ocean?

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#741

Don’t want to live in Africa. Which is where we came from supposedly.

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#742

Don’t waste your money on expensive EVOO or ‘high polyphenol’ olive oil!

EVOO is one of the biggest scams right now, based on current information. Sorry not sorry.

You can buy no-added sodium olives. Eat a couple of olives and get more polyphenols than in daily consumption of Bryan Johnson’s high polyphenol EVOO! Not to mention the better fat composition, and benefits in rct’s with canola over olive oil.

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#743

If you want to reduce apob, evoo may be a better bet than canola oil.

“Results of this study showed that CO consumption significantly reduced TC (-7.24 mg/dl, 95% CI, -12.1 to -2.7), and LDL (-6.4 mg/dl, 95% CI, -10.8 to -2), although it had no effects on HDL, TG, Apo B,”

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#744

I have to say I’m impressed by his new longevity supplement coming out. Great price too.

It has Creatine, Ca-AKG, Glucosamine, Taurine, Glycine, L-Lysine, Ashwagandha, L-Glutathione, L-Theanine, Hyaluronic Acid, Vitamin C, and Magnesium Citrate in decent dosages.

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#745

Obviously just because there was no statistical difference between betweeen CO and OO does not mean olive oil is likely to be better than canola oil to reduce apoB! The complete opposite…

First of all, canola oil reduces LDL better compared to olive as shown in the study, which is highly correlated with LDL. Dr. Oliver Zolman consider apoB and LDL to be equal.

Second. PUFA’s decrease apoB more than MUFA’s. Canola oil is high in PUFA’s.

Third. Canola oil has half the amount of saturated fat. And that increases apoB / LDL.

#746

It’s good they see the importance of keeping LDL / apoB low.

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#747

The full list of products coming out from Bryan’s company:

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#748

Pretty good multivitamin product here. I’d like it more if there were no Vitamin E at all but I don’t think the amount is high enough to be toxic. There’s also no magnesium or Vitamin K2 unfortunately, probably because his other products have those instead.

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#749

Full nutritional information for one day of eating:

Looks good.

Product_Nutrition_Facts.pdf (72.7 KB)

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#750

Which study are you referring to?

#751

Since this is an American product, there are 2 possibilities:

  1. They needed to remove all the LDL and cholesterol-lowering ingredients in the red yeast rice to comply with FDA standards.
  2. They are not in compliance with FDA standards.

If it’s #1, then you are wasting your money. If it’s #2, then they are doing something illegal, but as a consumer, who cares? I’ll assume #1 for now, and pass on this and just take my Bempedoic Acid. Red Yeast Rice is just a statin as statins were developed from it.

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#752

No, if you read the study it wasn’t comparing Canola with OO. It was looking at the impact of Canola Oil as an intervention “compared to sunflower oil and saturated fat”.

Not sure which study you’re referring to. But i think you (and most people) agree that apo B is the most relevant measure for atherosclerosis. We shouldn’t pick and choose measures to support an a priori belief.

And yet canola oil doesn’t reduce apo B. Maybe there’s a reason for that.

And yet canola oil doesn’t reduce apo B. Maybe there’s a reason for that.

If you want a good summary of the RCTs on olive oil and how it improves inflammation, bp and blood glucose, weight etc this is decent and recent:

And re blood lipids it interestingly states: "
While a diet that includes vegetable seed oil may decrease LDL more than EVOO, a diet that includes daily EVOO will produce healthier LDL as the particles will be larger and are less likely to be oxidized. In addition, EVOO has been shown to decrease apo protein B-100 indicating fewer LDL particles."

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#753

https://www.tandfonline.com/doi/abs/10.1080/10408398.2022.2100314

I don’t care whether they couldn’t detect apoB differences if they detected LDL. Those are pretty much the same to me. I use them interchangeably all the time.

My prior is that canola is better because it is lower in saturated fats and higher in PUFA’s. This study confirms it.

#754

Well worth reading up on the difference. And they’re certainly not interchangeable. The size and “quality” of the ldl-c can vary enormously. And things like fish oils and Evoo have a massive impact on the size and quality of ldl-c.

Peter Attia has an easy intro podcast on this (most recent Dayspring one I think). But if you want the literature, this would be a good place to start reading (“The Debate is Over”):

Apolipoprotein B vs Low-Density Lipoprotein Cholesterol and Non–High-Density Lipoprotein Cholesterol as the Primary Measure of Apolipoprotein B Lipoprotein-Related Risk: The Debate Is Over | Acute Coronary Syndromes | JAMA Cardiology | JAMA Network.

There’s even an argument that the ratio between apo b and ldl-c is more predictive. Suggesting that the amount of ldl-c is less important than the particle size and other qualities.

I’d be surprised if anyone recommended canola oil over ev olive oil after properly reading the literature on apo-b vs ldl-c.

And yet canola doesn’t benefit apoB, there must be a reason for that. If the volume of ldlc goes down, but the number of apoB particles stays the same, then it suggests that you’re shrinking the size of your ldlc particles. The research strongly indicates that that’s not a good thing. Compared to evoo, canola oil is also likely to lead to more oxidation of ldlc. Remember that sunflower oil was once thought to be healthy because it was low in saturated fats and high in pufas. But nobody has thought like that since the 90s.

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#755

From my experience I had the lowest apoB with berberine + canola oil vs. statin + olive oil. I will try now with statin + canola oil. Canola oil tastes great when mixed with berries to a smoothie.

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#756

n=1

And remember the other benefits of evoo. Don’t forget to monitor BP, inflammation, blood glucose etc

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