#745

Obviously just because there was no statistical difference between betweeen CO and OO does not mean olive oil is likely to be better than canola oil to reduce apoB! The complete opposite…

First of all, canola oil reduces LDL better compared to olive as shown in the study, which is highly correlated with LDL. Dr. Oliver Zolman consider apoB and LDL to be equal.

Second. PUFA’s decrease apoB more than MUFA’s. Canola oil is high in PUFA’s.

Third. Canola oil has half the amount of saturated fat. And that increases apoB / LDL.

#746

It’s good they see the importance of keeping LDL / apoB low.

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#747

The full list of products coming out from Bryan’s company:

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#748

Pretty good multivitamin product here. I’d like it more if there were no Vitamin E at all but I don’t think the amount is high enough to be toxic. There’s also no magnesium or Vitamin K2 unfortunately, probably because his other products have those instead.

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#749

Full nutritional information for one day of eating:

Looks good.

Product_Nutrition_Facts.pdf (72.7 KB)

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#750

Which study are you referring to?

#751

Since this is an American product, there are 2 possibilities:

  1. They needed to remove all the LDL and cholesterol-lowering ingredients in the red yeast rice to comply with FDA standards.
  2. They are not in compliance with FDA standards.

If it’s #1, then you are wasting your money. If it’s #2, then they are doing something illegal, but as a consumer, who cares? I’ll assume #1 for now, and pass on this and just take my Bempedoic Acid. Red Yeast Rice is just a statin as statins were developed from it.

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#752

No, if you read the study it wasn’t comparing Canola with OO. It was looking at the impact of Canola Oil as an intervention “compared to sunflower oil and saturated fat”.

Not sure which study you’re referring to. But i think you (and most people) agree that apo B is the most relevant measure for atherosclerosis. We shouldn’t pick and choose measures to support an a priori belief.

And yet canola oil doesn’t reduce apo B. Maybe there’s a reason for that.

And yet canola oil doesn’t reduce apo B. Maybe there’s a reason for that.

If you want a good summary of the RCTs on olive oil and how it improves inflammation, bp and blood glucose, weight etc this is decent and recent:

And re blood lipids it interestingly states: "
While a diet that includes vegetable seed oil may decrease LDL more than EVOO, a diet that includes daily EVOO will produce healthier LDL as the particles will be larger and are less likely to be oxidized. In addition, EVOO has been shown to decrease apo protein B-100 indicating fewer LDL particles."

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#753

https://www.tandfonline.com/doi/abs/10.1080/10408398.2022.2100314

I don’t care whether they couldn’t detect apoB differences if they detected LDL. Those are pretty much the same to me. I use them interchangeably all the time.

My prior is that canola is better because it is lower in saturated fats and higher in PUFA’s. This study confirms it.

#754

Well worth reading up on the difference. And they’re certainly not interchangeable. The size and “quality” of the ldl-c can vary enormously. And things like fish oils and Evoo have a massive impact on the size and quality of ldl-c.

Peter Attia has an easy intro podcast on this (most recent Dayspring one I think). But if you want the literature, this would be a good place to start reading (“The Debate is Over”):

Apolipoprotein B vs Low-Density Lipoprotein Cholesterol and Non–High-Density Lipoprotein Cholesterol as the Primary Measure of Apolipoprotein B Lipoprotein-Related Risk: The Debate Is Over | Acute Coronary Syndromes | JAMA Cardiology | JAMA Network.

There’s even an argument that the ratio between apo b and ldl-c is more predictive. Suggesting that the amount of ldl-c is less important than the particle size and other qualities.

I’d be surprised if anyone recommended canola oil over ev olive oil after properly reading the literature on apo-b vs ldl-c.

And yet canola doesn’t benefit apoB, there must be a reason for that. If the volume of ldlc goes down, but the number of apoB particles stays the same, then it suggests that you’re shrinking the size of your ldlc particles. The research strongly indicates that that’s not a good thing. Compared to evoo, canola oil is also likely to lead to more oxidation of ldlc. Remember that sunflower oil was once thought to be healthy because it was low in saturated fats and high in pufas. But nobody has thought like that since the 90s.

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#755

From my experience I had the lowest apoB with berberine + canola oil vs. statin + olive oil. I will try now with statin + canola oil. Canola oil tastes great when mixed with berries to a smoothie.

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#756

n=1

And remember the other benefits of evoo. Don’t forget to monitor BP, inflammation, blood glucose etc

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#757

Like I’ve said in other threads, 1 olive has more polyphenols than 2 tbsp of high polyphenol EVOO, it makes no sense to get it from a high caloric source.

#758

That doesn’t logically follow. Your logical error is to assume that we are trying to maximize polyphenol intake from a single olive product.

The question isn’t whether to eat an olive vs olive oil. I eat both.

Given that we need to consume oil / fat, the question is: which oil/fats are best to consume.
When it comes to ev olive oil versus canola oil, the evidence is pretty clear in favor of olive oil.

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#759

The study showed that canola oil decreases LDL in comparison with olive oil, but with no statistical significance for apoB.

The best way to know is to test it.

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#760

This discussion is ridiculous. Both olive oil and canola oil are perfectly fine alternatives to saturated fat sources and neither of them will move apoB by much.

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#761

Ok, i see you’re not receptive to the research, so I won’t repeat it. But I think it’s helpful to have laid it out for others.

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#762

Why do you think EVOO is better than canola oil for reducing apoB? And when replacing what, like saturated fat, or do you have a trial showing EVOO decrease apoB when replacing canola oil?

#763

:grin: Not sure why it’s ridiculous. This site is exactly the place to discuss the nuances of whether evoo or canola is better.
After all, if you’'re interested in Bryan Johnson’s protocol, you’re probably interested in the blood pressure, blood sugar and apo-b advantages of extra virgin olive oil. And you probably probably care about oxidation and size of ldl-c particles.

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#764

Read the papers i linked above. EVOO reduces apob. Canola doesn’t.