The weirdness of n=1
Today I have to brag a little:
It’s about 7 weeks since I began a vacation from rapamycin and things just continue to improve.
Today was my semi-annual check and my doctor, who has zero bedside manner, said: “That I was an exemplary example for someone my age.”
The only disagreement we had was over metformin. He wanted to take me off of it because my A1c levels have been consistently below the pre-diabetes range. (Yeh, because I have been taking metformin!) As I have posted before: Metformin may be the only proven life extender besides rapamycin and has other health benefits than lowering your A1c levels.
My blood pressure at the medical center was 93/60.
So, my doctor began quizzing me; Do you feel dizzy when you get out of bed or stand up after sitting for a while? Answer: No
How do I feel in general? Answer: Great.
At the gym I go to there are very few men that are as fit as I am. But I would say it’s less than 1 in a hundred. At Walmart, it’s probably less than 1 in a thousand of any age.
Fortunately, when I was young I was actively jogging and playing tennis when I could. I have been going to the gym regularly for the last 15+ years since retirement.
Rapamycin may help me live longer, but most of my results are due to:
Exercise
Diet
Metformin
Atorvastatin
Melatonin
And last, but probably not least, is the boatload of various supplements I have been taking throughout most of my life.
My points are: Rapamycin seems to continue its good works even after stopping.
It is really better to start taking care of yourself when you are young.
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What I hope to be doing in my 70s and 80s (though with friends, not solo):
Will Steger says, “Expeditions have kept me young.” This spring, at the age of 77, he set off on another two-month solo canoe-sled trip above the Arctic Circle.
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Why I think Rapamycin will turbocharge this trend of people pushing the athletic limits at older ages: Imagine all the people identified in this thread exercising as they have been, but also taking rapamycin…
Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats
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Still running at age 100
There was a good interview with Mike Fremont on the RichRoll podcast:
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Don’t see too much inevitable sarcopenia going on there.
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Yeah, I’ve seen it before. Mike is testimony to the power of a whole food plant based diet 
jakexb
#102
Super inspiring stuff. But also the fact that existence of people like this leaves people in amazement speaks to how incredibly rare it is.
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For now, at least 
. I suspect many of the people visiting here will be even more successful than these people over the next 50 years, in maintaining their health.
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And yet, the life expectancy of the average American is dropping yet again.
Here’s to those of you on this forum who will live far longer than average!
P.S. I’m not sure if you want to raise up the members of Rolling Stone as paragons of health and longevity as in the article!
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And a little humor, “Never give up, no matter what your age…”
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It truly is a heartwarming article. I want to be just like him when I am 110. 
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