Thanks, looks good to me.
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KarlT
#31
Not to mention, there’s no control group.
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Here’s your control group:

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More on Robert’s regimen:
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KarlT
#34
Lol. We’ll have to evaluate impact of plastic surgery on face aging.
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Add David Sinclair to the list…
The newly released Peter Diamandis video, at the point where David Sinclair says he’s taking rapamycin (“on and off”)
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arugula
#36
I would not trust any of those online facial aging indicators, or photos, or even videos. So much depends on lighting, camera angle, focal length, etc.
You have to see these people in person and look for telltale signs of surgery.
People falling out of their chairs when you tell them how old you are is gratifying.
But realistically, it’s only telling us that most people’s faces are aging prematurely when ours are not.
Edited to add, Sinclair looks to have had facelift, browlift, resurfacing, botox, and maybe even some type of filler or fat transfer. People throw dirt on all of it, but I am a strong believer in the mind-body-mirror connection. If you see youth when you look in the mirror, it changes the way you think about yourself.
Even Botox alone can be a game-changer. By smoothing the surface, it increases skin reflectance and luminosity and can add a “wow” factor.
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Neo
#37
Did you ever evaluate getting one/research them, do the results seem real?
Seems like Katalyst or this one: https://visionbody.com/
may be the leaders rights now?
I know the current versions are not doing calf and shoulder muscles, but does anyone know if Katalyst covers glutes well?
(Want to make sure it is covering the largest muscles)
No - I haven’t done any other research on this. No immediate plans of action. But would like to learn more.
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Neo
#39
Got it. K, I’ll let you k ow if I do more research
/and or get one.
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Jonas
#40
Never had a botox but thinking of doing it for my frown lines as my dentist keeps telling me that botox keep other part of your facial skin “younger”. Is it true?
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Yes, this is something under discussion a lot on social media these days, and something being pushed by Allergan (botox manufacturers), and Derms.
they call it “preventative botox”…
There are no large scale clinical or observational studies of preventative Botox. One 2006 study looked at identical twins, just two people, over 13 years. One received regular Botox injections. The other did not. The researchers found that lines were “not evident in the regularly treated twin” where she had received injections, but did appear in her sister. The untreated areas of both their faces showed “comparable aging.” In a follow-up, when the twins were 44, the twin who received treatments did not have static lines at rest; her sister did.
A 2011 study looked at whether the effects of repeated injections reduce or eliminate forehead wrinkles long term. Every four months, a group of 45 women, aged 30 to 50, received small amounts of botulinum toxin in their foreheads. Doctors assessed them two years after they began treatment, once the last treatment would have worn off, and found that the neurotoxin significantly reduced their wrinkles.
The Downside: Cost, about $450 each series of injection, on average. Internalized Negative Beliefs about Aging & Beauty
“Neurotoxin injections are a huge cash cow for dermatology offices,” said Valerie Monroe, the former beauty director at O, The Oprah Magazine and the author of a Substack newsletter on beauty.
Alternatives do exist. Many doctors pointed to sunscreen or retinols, which can increase collagen in the skin and work to counteract the visible effects of aging.
And few women in their 20s and 30s have deep, static lines, which means they have little use for the so-called preventative injections. If you’re considering Botox in your 30s, seek a dermatologist who will talk to you about why you want the treatment. Sometimes, dermatologists will suggest patients wait.
Dr. David A. Colbert, the co-founder and head physician of the New York Dermatology Group, said he worries that some patients have internalized damaging messages about aging and beauty.
“It’s a pretty toxic, heavy message,” he said. “People don’t even really analyze it anymore. They’re just like: ‘I can’t get too many wrinkles or I just will look awful.’”
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arugula
#42
Yes, I would not want to be without it. If you are brave you can DIY. You’ll need to learn facial anatomy, etc. but it’s not nearly as dangerous as self-injecting with filler.
I would post a pic but I am too shy. So I will PM you if you do not mind.
Edited to add-- I did not get botox until 43, and then I skipped it for about 15 years because I couldn’t convince myself it was worth the money. But recently I started again and it is amazing me.
I doubt it is preventing wrinkles when started in youth. That’s probably a huge waste of money. Sunscreen and retin-A can take care of lines in youth and early middle age.
But Botox is frigging amazing after 55.
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Neo
#43
Ok, found this:
What muscles does the Katalyst System activate?
Katalyst is a full-body workout that stimulates all major muscle groups (arms, legs, back, chest, core, glutes) at the same time, even hard-to-reach muscles like back stabilizers. The impulses can reach up to 90% of the fibers within each muscle, more than twice what you could engage with conventional training.
Some people ask us about training certain muscles, such as calves and forearms. Directly stimulating these muscles with Katalyst would be difficult and potentially cause you to lose your balance. They are, however, indirectly stimulated through exercise movements and the nerves that run through your upper extremities.
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Neo
#44
Jonas
#45
Mark T. Bertolini (born 1956) is an American businessman who is the Co-CEO of Bridgewater Associates, one of the world’s largest hedge funds. He was previously the CEO of Aetna
Source: https://twitter.com/chrissyfarr/status/1705205408632127830
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RapAdmin
#46
Wow - @Krister_Kauppi , you want to add this guy to the list.
But - the Wiki article is old - he’s now at a company called Oscar Health, a health insurance company (that, as people in that twitter thread point out, does not cover rapamycin for longevity applications):
Bridgewater is a very famous hedge fund, formerly run by Ray Dalio. In fact I was just reading about the company last week:
More info:
3 Likes
Because?
“People with psychopathy crave power and dominant positions, experts say. But they are also chameleons, able to disguise their ruthlessness and antisocial behavior under the veneer of charm and eloquence”
“One route to grabbing power for the highly intelligent psychopath is to climb the corporate ladder.”
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Jonas
#48
I can’t find the interview though, you always come up with magic, maybe you can give it a go.
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@RapAdmin & @DeStrider: If you look at this image what would you guess Robert Nelsen’s rapamycin dose is? 6mg or 8mg?
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