#77

A lot say go for it. Personally, I think taurine in my coffee the past year led to a better DEXA score from osteopenia to normal. So taurine seems to be uneffected in my morning coffee dose N=1.

Taurine is a naturally occurring amino acid that’s important for the heart and brain. It’s also involved in other bodily functions, such as: Calcium signaling, Antioxidization, Cardiovascular functions, and Musculoskeletal and retinal development.
Some studies suggest that combining caffeine and taurine can improve: Cognitive performance, Physical performance, Balance, Agility, and Anaerobic strength.

However, other studies suggest that taurine might reduce the cardiovascular effects of caffeine. More research is needed to fully understand the interactions between caffeine and taurine.

1 Like
#78

so what is the conflicting study on it? I think there is conflicting papers/studies on NAC, which is why I am reticent on that. I’ve seen nothing but longevity for glycine. There are questions regarding its relationship with rapa though, for sure, which is why I’m not totally comfortable… I think it can enhance MTOR?

For me it clears my gut issues… One of my afflictions is IBS… and glycine for me has totally made that regular. But it also makes me more virile with energy, I’m thinking taking a quantity of glycine helps replenish my glutathione (if glycine can do that alone, I’m not sure). Isn’t is also involved in promoting creatine and collagen etc?

2 Likes
#79

that’s exactly what i meant. I thought substances that activate/enhance Mtor were supposed to be no good for longevity.

#80

Glycine activates MTOR but it is only a minor effect. Rapamycin limits MTOR in a big way.
The magnitude of effect size is the important factor. I still take glycine even on my Rapamycin days.

3 Likes
#81

Inulin necessary if you already eat high fiber healthy meals?

1 Like
#82

Not sure, but some suggestion that inulin and other prebiotics are valuable for short chain fatty acids.

1 Like
#83

A good podcast on fiber generally, and short chain fatty acids.

2 Likes
#84

Is anyone doing this? You are already in a fasted state.

Considering doing this with 1mg Rapa

Screenshot 2024-12-21 at 7.01.16 AM
Screenshot 2024-12-21 at 7.01.16 AM1920×1368 121 KB

1 Like
#85

see Trying a daily Rapamycin Dose Change

and Daily Rapamycin Microdosing?

and What exactly is the strong argument against daily dosing for rapamycin?

1 Like
#86

1.5 liters of French press coffee with 2 servings of collagen peptides …split between two people; usually done by 8’sh. We do not drink anything caffeinated after that the rest of the day. The collagen is in part to provide glycine to accompany the NAC supplements we also take in the morning.

5 Likes
#87

Now I’ve added 7 mushroom blend with lions mane.

1 Like
#88

Bryan Johnson published his latest edution of morning routine.
I guess many of us already follow the components like biophotomodulation, meditation and exercise.
Does anyone subscribe to his BluePrint branded supplements?
He claims his aural temparture to be 94.5.
I am going to try checking mine.

#89

I take his essential capsule and softgel.

I had switched to buying the softgel components separately and then regretted it and switched back. It saved almost no money and was a PIA to take so many things

Here they are:

image
image1316×1550 146 KB

image
image1255×1246 178 KB

3 Likes
#90

I’ve updated my morning coffee routine… with a few more ingredients.

Coffee (Pour over)

  • Milk to cool it down a bit
  • Inulin
  • Collagen Powder
  • Lions Mane mushroom powder
  • Cacao powder
  • Creatine monohydrate
  • Astaxanthin powder

In each case, for simplicity, I add a moderately heaping tablespoon of the ingredient and stir. This is typically about 5 to 10 grams of material, depending on the product. I do a flat tablespoon of astaxanthin powder, so around 3 to 5 grams.

I added the Lions Mane mushroom powder about a month ago as I came across it on Amazon and thought I’d try it.

This is also a trial with the astaxanthin. It turns the entire concoction a dark red color. And tends to turn your poops red too. I brush my teeth after the coffee as I get the feeling my teeth could turn red also, if I went on too long with this protocol and didn’t brush my teeth immediately afterwards.

I’ll do a blood test in a few months and report on results.

il_fullxfull.4748062728_6c8r.jpg
il_fullxfull.4748062728_6c8r.jpg1850×1850 87.5 KB

7 Likes
#91

I don’t drink coffee. I’m really unproductive.

#92

@RapAdmin No TMG or Glycine? Relying on the collagen?

(I assume you’re taking taurine later in the day?)

Also, what Astaxanthin powder do you use? Can you link to it? Are you sure the Astaxanthin is being absorbed by your body as it tends to be fat soluble? Or is that what the milk is for?

#93

Any reason (besides taste) to go with Cocoa powder vs Cacao powder?

#94

No TMG, and yes, just the glycine from the collagen.

And @Nick1 , sorry my typo - I’m using Cacao powder, from Costco, just because it was available and reasonably priced.

I ordered a multi-kg synthetic astaxanthin sample from a manufacturer (DSM) … so not something most people would want to do. Astaxanthin, Natural vs. Synthetic - Your Thoughts?

Now that you mention it, I may not have enough fat at time of consumption… I just did a search on ChatGPT to see how much fat I would need and it seems to suggest I likely need more…

Yes, astaxanthin is a fat-soluble compound, meaning it requires dietary fat for optimal absorption. To maximize its bioavailability, you should take it with a meal containing healthy fats.

How Much Fat is Needed?

  • At least 5-10 grams of fat per serving is ideal.
  • Higher-fat meals (15-20g of fat) may further enhance absorption, but diminishing returns exist.

Best Fat Sources for Absorption

  • Avocados (Healthy monounsaturated fats)
  • Olive oil (Extra virgin, cold-pressed)
  • Nuts & Seeds (Almonds, walnuts, chia, flax)
  • Fatty Fish (Salmon, sardines, mackerel)
  • Eggs (Especially pastured or omega-3 enriched)
  • Coconut Oil or MCT Oil (Fast-digesting fat source)

Scientific Basis

  • A study showed that taking astaxanthin with a meal containing fat significantly increased blood levels of the compound compared to taking it on an empty stomach.
  • Lipid-based formulations (like astaxanthin in oil-based softgels) already improve absorption, but additional dietary fat can enhance it further.

Optimal Timing

  • Take with a main meal that contains fat (e.g., breakfast or dinner).
  • Avoid taking it on an empty stomach or with a low-fat meal, as absorption is poor under those conditions.
2 Likes
#95

Got it. I have used Volupta brand from Costco. Apparently its in top 5 brands for low chromium content amongst Cacao podwers.
I also get Cocvitae brand when its on sale. It does taste better.
I would try astaxanthin in my morning protein shake which essentially is Levels Whey Protein+1 tbsp of EVOO+ 1 tsp of cinnamon that way absorption is taken care of.

2 Likes
#96

I love seeing what others are doing, so thank you for sharing.

I have questions!!! For you or anyone!

  1. I find the world of mushrooms overwhelming, so is there a stand out reason you chose lions mane vs a blend or another option?

  2. I imagine there might not be an answer to this, but does anyone feel that vegan collagen might work. I am taking vecollal and I’m not sure I can get over my ick factor to take the real stuff. I’ve been toying with trying because I keep seeing how good it is for us… I’m just not used to consuming animal products.
    https://www.vecollal.eu/

I currently use the following ‘as seen on rapamycin news’ mushrooms

And tremella because a few have raved about its skin benefits.