A kidney cancer vaccine candidate has shown great promise in an early Phase I trial published this week.

Research paper (open access)

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

https://www.nature.com/articles/s41586-024-08507-5

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Great news! Hopefully it can be applied more broadly and to more cancers. It’s stories like this that make my heart glad.

This seems ground breaking, but I have heard some experts say it will have limited application. Hopefully they’re wrong.

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Wouldn’t it be great if we had a similar pancreatic cancer vaccine? This cancer is notoriously hard to detect and it rapidly metastasizes. Perhaps people of a certain age could take it periodically (assuming no severe side effects) to reduce any potential cancer, not just known cancers. Just daydreaming here. Here are two therapeutic vaccines in development for established pancreatic cancers:

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