This is a good attempt (thank you!); the problem I see with it is that there is a high probability of double-counting: people who initially got a script from one doctor and moved to another, or to an online pill mill telemedicine platform, or to importation from offshore — and every alternative permutation of sequence.

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Double counting is a potential issue. I haven’t polled people on whether they have switched doctors or shifted where they get their prescriptions over time.

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Brian Kennedy estimates up to 100,000 people could be taking rapamycin off label now (in this new video): https://www.youtube.com/watch?v=z4AeCkD2650

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Sounds like Brian Kennedy is positive on rapamycin here. Wonder if he is taking it himself. He also seems to be on NAD supplements.

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That seems unlikely to me, since the Rapamycin thread for buying rapamycin has 137,000 views and that’s includes people who are curious or view it multiple times, not people who take it regularly.

I’d guess it’s like 30% of the registered users here, which is 1433, add a couple of thousand users and it’s maybe 5,000 users in total who use it regularly. That’s also a third of Matt Kaeberlein’s subscribers.

I might be scribbling patterns in the sand looking at astrology signs here, but

100,000 feels way too high.

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FWIW, I have been repeatedly surprised by how many of my friends and even casual acquaintances admit to using rapamycin. Just the other week, I had a brief conversation with a casual acquaintance in the park where I jog - he goes there to walk his dog. Years ago, as an animal lover, I have struck an aquaintence with him based on that dog. Last week he was sharing his worries about the health of the elderly dog. I cautiously ventured that there is this drug, rapamycin which has been shown in dogs to… before I could finish the sentence, he knew all about it, and informed me that in fact he is taking rapamycin himself! And so we had a brief exchange about rapamycin in humans, effects on exercise and so on, lol. Importantly, he was not aware of rapamycin news website, so I don’t think it’s safe to assume most rapa users frequent this place.

I swear this happens so often with random people in random situations, that I started to ponder the meaning of the little factoid Matt Kaeberlein shared in one of his podcasts, that the nickname for rapamycin among those in the know, is “vitamin R”. Hmm, perhaps rapamycin is headed for the frequency of use of common vitamins taken by masses of people in everyday life. Something we laugh about with my wife after learning that yet another person transpires to be a rapa user… it’s just another vitamin to people these days, lol!

Of course, I might be living in a bubble here in West Hollywood, but I’ve had these encounters elsewhere too.

All anecdotal of course, but I feel the rapa cat is well out of the bag, and scratching. This didn’t use to happen as often even a couple of years ago, but I feel rapa has now reached a critical mass and soon it’ll be old hat. The 100K number feels plausible to me, if not an undercount, to be honest. But who knows…

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I tend to agree with @AnUser: 100k seemed way too high to me. But, like @CronosTempi, I had two recent encounters (one in the South of France and one in Dubai) with people in their 30s taking rapa. They only mentioned it when we started to discuss health and longevity. They’re not active on this forum, although I’m sure they read some posts here before making the decision to start it.

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