#41

Check this thread for TUDCA: UDCA (ursodiol) / TUDCA for healthspan and lifespan?

I don’t take it but for high AST and other liver markers it seems to work well and to be safe.

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#42

No, not an idiot, but I don’t think you’ll get good cycle advice here and this forum isn’t friendly towards PED use, so advice will be skewed and tends to be over cautious and uninformed on this subject. I’d suggest joining Chase Iron’s discord or at least hanging out on meso-rx, professional muscle, t-nation, steroid source talk, enhance genetics etc.

That said, 52.3% with that RBC sounds like a hydration issue (what is the hemoglobin level?), and most manage it also with daily cardio that includes at least some HIIT. That’s considered mandatory if you’re going to use gear. But nobody doing cycles is worried about 52.3%. There’s a lot of discussion on this topic on excel male dot com and by YouTube doctors. None are worried about erythrocytosis causing clotting, but some worry about arterial shear stress over time. But 52.3 isn’t enough to worry about regardless.

Your liver enzymes aren’t bad for what you’re doing. Add NAC. Take som astragalus for your kidneys, but your eGFR probably dropped because of muscle turnover and mass. Get a cystatin C and use the national kidney foundation calculator.

Estradiol is fine for your T levels, but does put you in gynecomastia territory. Same comment on the prolactin. I’d knock the estradiol down below 60, maybe to 40.

It seems like your biggest issue is that you’re wasting time doing this and stressing yourself body for no good reason if you’re not eating enough. You can’t be afraid to gain some fat. I’d discontinue if you can’t maintain a surplus and train very hard because otherwise you’re just spinning your wheels.

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#43

Thank you, this is all very helpful information. @AgentSmith

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#44

@jnorm ezetimibe will bump your liver enzymes. An AST of 42 isn’t too bad but if you are concerned you can take 1/2 or even a 1/3 of that 10 mg dose and get pretty much the same effect on your lipids. That will likely allow your AST to return to normal. I’d do that before I added TUDCA.

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#45

What dosage are you taking to get total T of ~2400, if you don’t mind me asking?

#46

400/week of the cypionate ester. IM’ing EoD.
That was my trough iirc.

#47

I’ve always wondered how it scales. Does T go up linearly with dose, or is there a curve? Probably individual.

#48

One more piece of evidence: Cardiovascular Health - #1725 by RapAdmin

Pooled analysis revealed that combination LLT significantly more effectively reduced the LDL-C level from baseline (mean difference, −12.96 mg/dL; 95% CI, −17.27 to −8.65; P<.001) and significantly reduced all-cause mortality (OR, 0.81; 95% CI, 0.67 to 0.97; P=.02), major adverse cardiovascular events (OR, 0.82; 95% CI, 0.69 to 0.97; P=.02), and stroke incidence (OR, 0.83; 95% CI, 0.75 to 0.91; P<.001), with an insignificant effect on cardiovascular mortality (OR, 0.86; 95% CI, 0.65 to 1.12; P=.26) when compared with statin monotherapy. The risk of adverse events and the therapy discontinuation rate were comparable between groups.

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