Rapamycin + Metformin

curt504 · 2025-05-13T16:18:18.206Z

desertshores:

taking 500mg in the evening

@desertshores and I see others are taking metformin in the PM. Any reasoning for not AM and in the PM?

Tnx curt

desertshores · 2025-05-13T21:05:52.369Z

It depends on how much metformin you are taking. If you are taking more than 500 mg of metformin, I would divide the dose.
My 500 mg prescription says evening.

DeStrider · 2025-05-13T23:54:53.631Z

I take mine in the evening as well. When I was taking 1 g, I split the dose between morning and night. I actually switched to Metformin XR which slowly releases metformin throughout the day in order to avoid GI issues. It’s a little more expensive though.

adriank · 2025-05-14T05:05:02.152Z

I had a strange reaction between jardiance and metformin… Might just be a coincidence. I’ll restart tonight with 500mg xr. My cgm does not go below 5…