My wife 74 is experiencing tender breast like during premenstrual? On 4mg for three week as of 2/12/23. Anyone else experiencing the same?

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Somewhere on this site a user said their post-menopausal mother got spotting after several weeks of rapa. I believe the woman was in her mid-60ā€™s. There are several threads here that discuss the effects of rapamycin on woman vis-Ć -vis menstruation and menopause. I recommend those threads as they are full of useful information.

https://spotify.localizer.co/search?q=Menopause

Wow - we havenā€™t had that reported before at that age I donā€™t think. You may want to post on this thread following as all the people participating in the thread get the message emailed to them, or at least a notification: Women Taking Rapamycin for Enhanced Fertility / Menopause Prevention?

And, remember to always be safeā€¦ perhaps birth control is not something only for the young! Assuming, of course, you donā€™t want additional new children in your mid 70s :slight_smile:

Fwiw Iā€™m 53, have only been on rapa for 2 months and experienced this briefly a couple of times.

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Not sure what you experienced.

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Breast tenderness similar to what I experienced prior to menopause.

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I started Rapa march 19th and my breasts are more tender than ever. Itā€™s driving me nuts. Iā€™m seeing my doctor next week. Maybe itā€™s perimenopause for me? Iā€™m 47. Mammogram is clear.

@Skyzercise, if itā€™s any consolation my sore breast issue resolved quickly and hasnā€™t returned. I started taking rapa on 1/9/23.

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Thatā€™s good to know, thank you!

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Fwiw : my birthyear is 1976 and started in April 2023 with rapa (started to have months without a period about a year ago);

my last period ( very regularly) started on Monday 4 September very heavily and on Tuesday 5 September I took my first dose of 3 mg ( going slow due to annoying skin rashes, but finally I took courage as I didnā€™t have any skin effects after last 2 mg dose)

My period has lasted until yesterday ( full 2 weeks; in addition first week very heavily) and this is the first time this ever happened to me ( both in terms of duration and intensity letā€™s say the first 7 days - usually lasts me 2,5 -3 days and cannot remember it ever being so heavy) . Will update the next months ( will go back to 2 mg for a while now)