这对于在座的每个人来说都是一个很好的机会，可以帮助推动雷帕霉素临床科学更快地向前发展。威斯康星大学 Lamming 实验室的 Dudley Lamming 今天早上给我发了这个信息。让我们通过参与来支持他的研究！这是长寿动力资助小组及其优秀团队资助的又一个好项目。如果您想更快地推动长寿科学向前发展，我们鼓励您向推动基金捐款。
“评估雷帕霉素作为 geroPROTECTor 的安全性和有效性”(RAP-PROTECT) 研究正在威斯康星大学麦迪逊分校启动。我们希望招募年龄在 30 岁至 90 岁之间的美国大陆成年人，他们正在或计划在医生的监督下服用雷帕霉素（西罗莫司）或依维莫司等类似物，以促进健康老龄化。
参与者将接受一次抽血并回答有关其健康状况的问题。
- 这仅适用于美国大陆的人们（您可以在美国大陆的任何地方）。
- 受试者需要有一位医生知道他们正在服用雷帕霉素，并负责帮助他们应对药物的任何影响。
- 抽血师会来到受试者的家中或工作场所并当场抽血。
- 这项研究从今天开始，直到所有血液样本完成后才结束。
- 他们计划完善全血转录组学和血浆脂质组学，以全面了解雷帕霉素的作用，然后对甘油三酯、衰老/炎症标志物和葡萄糖/胰岛素等物质进行针对性测定。
- 如果一切顺利的话，研究结果可能会在一年内公布
There is a compensation of a $25 gift for participants
如需参与，请立即向 RAP-Protect 团队发送电子邮件
通过电子邮件将以下信息发送给他们的团队：
- 姓名
- 年龄
- 性别（男/女）
- 雷帕霉素状态（目前服用是/否，多长时间？，剂量？）
- 如果您尚未服用雷帕霉素计划
- 您居住的城市/州
通过电子邮件发送至：
电子邮件： rap-protect@medicine.wisc.edu
（电子邮件不是一种安全的通信方式。请避免通过电子邮件发送其他敏感个人信息）
For more information, please contact the RAP-PROTECT study team by email, or at
电话：(608) 263-2475
研究小组组长： Dudley Lamming 博士
14 Likes
Melih
#2
You Americans are lucky…!
1 Like
Do you have to be in Wisconsin to participate?
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No - anywhere in the continental USA.
3 Likes
It says “under the supervision of a doctor.” Does that mean that those of us who are going rogue and ordering from India are ineligible?
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Yes - I suspect that is the case. I will check with Dudley and post an update here if anything changes.
3 Likes
Dudley responded with this, and I’ll update the main posting above too:
受试者需要有一位医生知道他们正在服用雷帕霉素，并负责帮助他们应对药物的任何影响。
Basically I think they need you to be operating under the care of a physician with regard to rapamycin, so that their butts are covered from a legal perspective if anything bad ever happened to you (this is likely part of the IRB requirement, from the University of Wisc.)
They don’t care where you get your rapamycin, just that you have a doctor who knows you are on rapamycin and can help you if you have any issues.
6 Likes
Email sent. Thank you for sharing!
3 Likes
Sent in…
I am directly under the care of my PCP who writes my rapamycin prescription. PCP - monitors my health through blood testing every 3-4 months.
Getting great care.
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KarlT
#10
Anyone know what they are looking for and what blood tests they will run?
1 Like
This just received by email.
Dear Mr Haxton,
We are delighted that you are interested in the RAP-PROTECT study. My name is Dr Cara Green, and I am one of the scientists involved in this study.
The next step is to set up a phone call to discuss the nature of the study and eligibility. If you are willing to proceed and are eligible, we will discuss informed consent.
Please provide a phone number and choose from the below a time that would work for me to call you. The call should take around 30 minutes.
If you could choose more than one time slot that would be helpful, as we have several people signing up and your first choice may be taken. If none of the time slots work for you, let me know and we can figure something out.
Thank you for taking an interest in our study.
All the very best,
Cara
6 Likes
Hello reader,
I’ve submitted my e-mail to you in order to be considered for your Rapamycin study.
In Palm Beach, FL; please phone T: 813 928 5223.
Thank-you, Jan Stein
2 Likes
Had my interview to participate in the research with Cara today… her first person interviewed… they are looking to have about 100 total in the pool.
Looks like I might be in… signed off for blood collection.
Was all wrapped up in a half hour.
We chatted about our interactions with Matt Kaeberlein they have something together in a few weeks. She lives on the Pacific coast.
Will keep you abreast of it all.
5 Likes
Bicep
#15
I sent it in last week and still have not heard back. Lucky Jason.
2 Likes
Name: GPA
Age: 60 years
Female
Taking Rapamycin (Sirolimus) since July 2021
Took 4 mgs once a week for 10 months, then increased to 6 mgs once a week.
No side effects ever.
I live in Rye Brook, NY
Email: pg…
My doctor who prescribes Sirolimus is Dr David Lans.
4 Likes
Hi Patti,
Welcome to the forums. I edited out your full name and email address so that you don’t get spam, etc. Generally we suggest you may want to remain anonymous here since we are discussing health situations here, to maintain a level of privacy.
2 Likes
Any idea what the blood analysis involves? What markers are utilized? Do they share results of blood tests and research at conclusion with participants?
I recommend you email/contact them on the detailed questions - above I mentioned:
Dudley’s response was:
We’re planning to perfecting whole blood transcriptomics and plasma lipidomics to get a global view of the effects of rapamycin, and then targeted assays on things like triglycerides, senescence/inflammatory markers, and glucose/insulin.
2 Likes
Can you share where you are ordering from? I am just starting and looking for a reliable source. Thanks so much
