That’s an interesting question. Obviously there are two parts to this. Potassium and Chloride. Is the issue Chloride or Potassium?
I think there is an issue about Potassium supplementation and maintaining the Potassium - Sodium balance.
I have never encountered anything about Chloride issues much that it is a part of some blood panels.
约瑟夫
#124
Use Mg chlorine, by IV lowers BP and used by several hundred reactions in your body.
Yes, I said IV.
Tell me more about this IV. How often do you do it? Cost?
How do you measure VO2 max? The Kenneth Cooper 12 minute test?
RPS
#127
I go to a clinic specialising in Vo2 max and Dexa scans.
Sorry, not sure what the method is called, but it is around 12 mins long.
JuanDaw
#128
No need for a lab.
To calculate your estimated VO2 Max results (in ml/kg/min) use either of these formulas:
-
Kilometers: VO2max = (22.351 x kilometers) - 11.288
-
Miles: VO2max = (35.97 x miles) - 11.291
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Full study below.
It should also be noted that the current analysis is not able to determine whether the mechanism of increased cancer risk with ARBs is related to the carcinogenic impurities recently identified in several ARB containing drug products.
The contrary opinion from
Franz H. Messerli, MD
Cardiology Today Editorial Board Member
University of Bern, Switzerland
Scroll down. Mersserli was responding to the author’s (Ilke Sipahi) article.
Why then are we not seeing a significant risk of cancer in numerous randomized CV trials? It is exceedingly unlikely that in a follow-up period of a mere 3 to 4 years, a minute increase in life expectancy of a few days to weeks will allow us to document an increased cancer risk. However, CV drugs are usually prescribed for years, even decades and the increase in life expectancy and thereby the risk of cancer becomes progressively more significant with time.
As to Dr. Sipahi’s assertion of ARBs being “inferior to many other classes of antihypertensives for prevention of mortality and cardiac morbidity,” we point to our analysis of almost 1 million patients published 3 weeks ago (Messerli FH, et al. Circulation. 2022;doi:10.1161/CIRCULATIONAHA.121.057835); in a head-to-head comparison with ACE inhibitors, ARBs showed similar efficacy in terms of death, CV mortality, MI, stroke and end-stage kidney disease.
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Metoprolol was the first choice of my cardiologist for controlling age-related blood pressure increase.
I like it because I have not had any side effects and it works well for me.
“Metoprolol works as well as other beta blockers for reducing high blood pressure, but is less likely to cause side effects. That’s because metoprolol works mainly on the heart.”
“In conclusion, this research seem to confirm a possible beneficial effect of β-blockers against the risk of cancer development.”
https://www.nhs.uk/medicines/metoprolol/common-questions-about-metoprolol/#:~:text=Metoprolol%20works%20as%20well%20as,works%20mainly%20on%20the%20heart.
https://www.tandfonline.com/doi/abs/10.1185/03007995.2013.772505
Neo
#131
Any update on your VO2 max @RPS , or anny else for using it now after 6ish months?
Neo
#132
A wearable cuff on wrist version below - anyone have any thoughts or even tried it?
HeartGuide is a clinically accurate, wearable blood pressure monitor
HeartGuide is the first clinically-accurate, wearable blood pressure monitor designed in the innovative form of a wristwatch, and is registered with the FDA as a medical device.
The design of HeartGuide involved more than 80 new patents that miniaturize the components for traditional oscillometric measurement, using an inflatable cuff within the watch band to take a blood pressure reading.
Over the course of any normal day, your blood pressure fluctuates. Monitor these fluctuations with clinical accuracy with HeartGuide. Collect, review and store your fluctuations as detailed, usable data, and develop a more thorough understanding of how your lifestyle directly impacts your heart health.
RPS
#133
Sorry, haven’t done another test yet. Hope to schedule it in before Christmas though.
1 Like
Neo
#134
More support for this wrist one - that has five clinical trials also from Peter Attia:
Not approved by FDA but available in Europe
3 Likes
Tomnook
#135
I can attest to the accuracy of the Aktiia after using it 24/7 for almost two years. It was a very fortunate purchase indeed - I’d assumed my bp was pretty much unchanged since I last tested it at home (I suffer badly from white coate syndrome) - how wrong I was! Made an appointment with my doctor who sent me straight to hospital with 220/100 readings. Four days later I managed to get discharged after showing the consultant the Aktiia printout which showed improvements compared with the hospital trolley machine which I was unable to get below 180 systolic which was their cutoff for discharging me. Four months later I was down to below 120 systolic and have remained there ever since. If anyone in the group would like to purchase one of these I’d be happy to order for you and ship since they are still Europe only atm I believe.
4 Likes
Adding 1g of potassium citrate and 3g of l-citrulline to my daily stack is dropping my blood pressure levels to very low levels. Nearly couldn’t stand up straight yesterday night.
J0hn
#137
Thank you for the recommendation I’ve just placed a bid on eBay for one
1 Like
A new blood pressure ring in development:
3 Likes
That strikes me as an even harder way of measuring it. Picking it up from movements in blood vessels on the wrist seems at least possible, but from a ring on a finger?
PHILADELPHIA – Intensive blood pressure control reduced dementia risk among individuals with hypertension, a randomized trial from rural China showed.
A village doctor-led intervention with a simple stepped-care protocol targeting a blood pressure under 130/80 mm Hg reduced occurrence of any dementia by a relative 15% compared with usual care over 4 years (1.12% vs 1.31% incidence per year, RR 0.85, P=0.0035).
The average 22/9.3 mm Hg greater reduction in blood pressure with intensive control also reduced incidence of non-dementia cognitive impairment by a similar degree (4.19% vs 5.02% per year, RR 0.84, P<0.0001), Jiang He, MD, PhD, of Tulane University in New Orleans, reported at the American Heart Association (AHA) meetingopens in a new tab or window.
3 Likes
RPS
#141
Just taken my third V02MAX test and now have some interesting results.
Between the 1st and 2nd test my very good 44.0 ml/Kg/Min moved up to 44.7
The third test after the same 10 month interval saw a big jump up to 47.7
I started to do a little bit more (very minimal) HIIT in the last 6 weeks so I believe this big impact is as a result of using a breath trainer. This is the one I have been using:-
https://www.amazon.co.uk/Powerbreathe-LSI-Plus2-Power-Breathe-Fitness/dp/B000NJMLPA/
Also, I would point out that I have been using it for only half the recommended amount i.e. I only do it once a day for 30 breaths instead of twice a day.
3 Likes
Neo
#142
Very interesting @RPS
Seems to be a bit of research behind it, see below
How much did you look into it before selecting this specific one?