#1

Risks and Benefits of Nicitinic Acid (NA), a NAD+ Booster

3 Likes
#2

Now a followup video from Dr. Greger about nicotinamide - sounds like megadosing is to be avoided.

Risks and Benefits of Nicotinamide (NAM), a NAD+ Booster

1 Like
#3

Thank you.

But: the dosage of niacinamide to inhibit SIRT1 for an adult man is estimated at around 4000 mg, based on achieving a plasma concentration of 0.5 mM, as used in cell culture studies.

In the same time: niacinamide offers significant benefits for skin health (perfect for managing any kind of eczema - both topically and as supplement), skin cancer prevention in high-risk individuals, osteoarthritis management, and phosphorus reduction in CKD dialysis patients.

→ pulsed intake of 100-500mg daily make perfect sense for „some“ individuals :))

#4

The series continues. NR doesn’t sound especially good.

Risks and Benefits of Nicotinamide Riboside (NR), a NAD+ Booster