Niclosamide mTOR 1

KFISH · 2022-04-20T22:35:12.872Z

Has anyone looked at #niclosamide?

Interesting mTOR 1Inhibitor

[From RapAdmin: This video is from a guy who is promoting it as an mTOR1 inhibitor - seems like he’s just a guy who wants to make money off it. Lets not promote him, lets look at the data on niclosamide)

RapAdmin · 2022-04-20T23:12:25.483Z

I cannot find a single study on Niclosamide and lifespan… seems like a huge, huge stretch to suggest this might replace rapamycin in any way.

en.wikipedia.org

Niclosamide

Niclosamide, sold under the brand name Niclocide among others, is a medication used to treat tapeworm infestations. This includes diphyllobothriasis, hymenolepiasis, and taeniasis. It is not effective against other worms such as pinworms or roundworms. It is taken by mouth. Side effects include nausea, vomiting, abdominal pain, and itchiness. It may be used during pregnancy and appears to be safe for the baby. Niclosamide is in the anthelmintic family of medications. It works by blocking the upt...

Here is some data on Niclosamide as it relates to mTORC1:

The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR

journals.plos.org

KFISH · 2022-04-21T09:30:07.683Z

I agree I don’t want to promote him but science is always asking questions could this supplement be a complementary to Rapa? Or is this just a guy trying to make money?