The quest for the fountain of youth may go back centuries, but it’s only in the past two decades that scientists may be close to finding it—at least as it pertains to yeast, flies, and mice.

The elixir of interest to both researchers and longevity seekers is the prescription drug rapamycin. Some anti-aging influencers like Peter Attia, a physician and popular podcaster who devoted a chapter to the drug in his recent bestseller, Outlive, are enamored by its possibilities. But whether it truly extends life and expands people’s disease-free years remains an unanswered question.

Years of research in mice have shown that rapamycin “is the most robust and reproducible drug” when it comes to increasing lifespan and slowing the aging process, says Matt Kaeberlein, a longtime rapamycin researcher at the University of Washington in Seattle

完整文章在这里: Can this ‘anti-aging’ drug live up to the hype? Here’s what we know. (NatGeo)

Could This Transplant Drug Add 5 Years to a Woman’s Fertility?

You don’t have to watch “The Substance” to recognize society’s obsession with antiaging: endless products promise to keep you looking younger on the outside. Additional tactics like eating particular diets or trying to boost your metabolism attempt to tackle antiaging from the inside out. But there’s one drug you’ve probably never heard of that many doctors feel confident can actually slow the aging process: rapamycin.

Several studies back up the claims, but until recently, most research has focused on people 50-years-old and older. Now, a new study claims younger women can benefit from taking the drug. Since it’s capable of extending fertility and delaying menopause, it would benefit women’s whole-life health in a multitude of ways.

So, what is rapamycin, and should you be taking it? Read on to learn more about the benefits and risks associated with the drug — and whether you should ask your doctor about it at your next visit.

Experts Featured in This Article: Zev Williams, PhD, is the director of the Columbia University Fertility Center in NYC.

Read full story: Could This Transplant Drug Add 5 Years to a Woman’s Fertility? (Pop Sugar)

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I’ve been looking for something not too science-y that would be good to share with a lay person. This NG seems to tick that box, so thx!

(If there is a better article or video, by all means…)

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The NatGeo article is a reasonably well-written and balanced article, and yes it would be great to share with a lay person. If a person is very health-oriented, and not too risk adverse, this might be tempted to learn more based on this article, in which case I’d point them towards the videos we have listed here: Best Videos Covering Rapamycin (part 2)

If the person is at all risk adverse they’ll look at the words “unproven in humans” and likely run for the hills, and completely ignore the fact that rapamycin has worked (at improving lifespan/healthspan) in every organism its been tested in, from yeast to worms, to flies, to mice, to rats and now in primates (marmosets)…

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I’ve been wanting a great video for that purpose for quite a while, so this is truly appreciated and will prove to be useful.

THX!

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