Seems like a new business opportunity; transplantation of brown fat (perhaps from young athletes?) to older people… :wink:

  • Brown fat, unlike white fat, burns calories and can boost exercise performance by improving blood flow to muscles during physical activity
  • Mice with enhanced brown fat lived 20% longer and showed 30% better exercise performance, with the benefits transferable through tissue transplantation
  • Rutgers researchers are developing a drug that could activate brown fat in humans, potentially helping people maintain physical fitness as they age

The new research paper published in the journal Aging shows that brown fat isn’t just for keeping us warm—it actively contributes to better exercise performance and potentially extends our healthy years. The paper, authored by Dorothy E. Vatner, Jie Zhang, and Stephen F. Vatner from Rutgers New Jersey Medical School, offers a fresh perspective on fat tissue and its surprising connections to exercise capacity and longevity.

“Exercise capacity diminishes as you get older, and to have a technique that could enhance exercise performance would be very beneficial for healthful aging,” said Stephen Vatner, university professor and director of the Cardiovascular Research Institute in the medical school’s Department of Cell Biology and Molecular Medicine and senior author of the study, in a statement. “This mouse model performs exercise better than their normal littermates.”

Open Access Paper:

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Brown fat transplants or ice baths? (Cold exposure also increases brown fat). I’m not sure which one I’d prefer. Perhaps I’ll wait for the Rutgers team to develop their drug.

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