Is instant coffee less healthful or not?

AlexKChen · 2025-08-16T17:02:32.638Z

Rhonda Patrick is more positive
I think the best meta analysis i saw showed neutral effect (but not neutral at the quantities I drink)

Probably a low quality study

News-Medical – 17 Jun 25

Instant coffee may damage your eyes, genetic study finds

Researchers used genomic and Mendelian randomization analyses in over 500,000 individuals to reveal a statistically significant causal link between instant coffee intake and increased risk of dry age-related macular degeneration (AMD). No such risk...

AustraliaLongevity · 2025-08-17T07:46:41.505Z

I wonder about the quality of the instant coffee? I prefer brewing with a machine anyway, tastes better.

A_User · 2025-08-17T07:50:01.758Z

genetic predisposition to instant coffee intake

Is this really a thing? I’m skeptical if we don’t know the mechanism of action, what the genes were and possible pleiotropy (confounding). Generally skeptical of nutrition MR.