From AgelessRx - re SGLTi mini trial ahead of hopefully adding to their product offering.
(SGLTi is one of the best performing compounds in the NIH/NIAs ITP).
We have started the recruitment process and you are invited to participate in an exclusive 2-week study that examines the efficacy and tolerability of Canagliflozin on glucose biomarkers. We are offering 20 interested patients access to 1-week of Canagliflozin Rx, Urine Test Kits, and a Continuous Glucose Monitor, and will provide you with your urine glucose and average glucose biomarker results.
I just had my screening call for this (very quick and simple) and think Iām going to do it.
Seems like a great way to help the movement forward. If AgelessRx (a) publishes on SGLTiās use in healthy individuals, even if very short study, (b) they demonstrate that half / eod dosing is works re the glucose modulation part, and especially (c) they as a leading, mainstream longevity medicine provider start offering Cana (or other flozin) as part of their services/products it could help generate much more interest for SGLTi as a gerotherapyā¦. (and may lead to HealthSpan and other competitors following suit and that driving even more interest as they both do social media marketing, etc)
ā¦ anyone else interested?
you would do everything from home, they send you the things home and everything is covered by them/no cost to you.
Everyone does both a treatment week and a control week - so you are guaranteed to test Cana, not risk that you are only in some control arm.
The main exclusion criteria is to not be taking another glucose lowering med (Acar, Metformin, GLP-1a).
To show interest/sign-up just send a one sentence email to: research@agelessrx.com
(I have no affiliation, just think this is important for our mission and the longevity field).
#Whole email from AgelessRx:
We have started the recruitment process and you are invited to participate in an exclusive 2-week study that examines the efficacy and tolerability of Canagliflozin on glucose biomarkers. We are offering 20 interested patients access to 1-week of Canagliflozin Rx, Urine Test Kits, and a Continuous Glucose Monitor, and will provide you with your urine glucose and average glucose biomarker results.
What does it mean to participate?
Participation in this study is free! You will receive a 1x Continuous Glucose Monitor, 4x Urine Test Kits, and 1x week of Canagliflozin Rx. During the study, we ask that you measure blood pressure readings, answer online surveys, complete urine test kits, wear a continuous glucose monitor, and document your macronutrients during the study. Donāt worryā weāll provide you with everything you need, right to your door.
What is Canagliflozin?
Canagliflozin, commonly known as Invokana, is an FDA-approved medication used in the treatment of type 2 diabetes. It belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors. The drug works by inhibiting glucose reabsorption in the kidneys, promoting its excretion through urine, thereby lowering blood sugar levels. Similar to rapamycin, canagliflozin performed favorably at extending lifespan in mice in the Interventions Testing Program (ITP). Read more about that here.
In our study, we aim to explore the efficacy and tolerability of canagliflozin in healthy individuals when administered intermittently.
How can I get started?
Act fast! This study will only enroll 20 individuals (but will pave the way for future projects).
āClick Here to Take The Next Step ā
*Please note that individuals based in these states will not be available to participate in this study: AL, AR, KY, LA, MS, NC, ND, NY, and SC.
Thank you for your time.
Kindly,
The AgelessRx Project Team
Their email to show interest and sign up (after a short intro call) is: research@agelessrx.com
