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Nice article. I use nasty chemicals, but am usually only exposed a few days of the year and I take obvious precautions. It would be good to find out. I didn’t see what the cost was for the whole thing.

a surprisingly large number of PCBs/dioxins decelerate GrimAge epigenetic aging [though with borderline significance]: PCB118 and 1,2,3,4,6,7,8-Heptachlororodibenzo-p-dioxin (HpCDD)]

fwiw, dioxins are one of the most canonical hormesis-inducers…

cadmium accelerates it, but NS in non-smokers

[grimage also isn’t the best epigenetic age meter anymore, so lets see if results hold on more accurate one]


14.Tuomisto J., Tuomisto J.T. Is the fear of dioxin cancer more harmful than dioxin? Toxicol. Lett. 2012;210:338–344. doi: 10.1016/j.toxlet.2012.02.007. [DOI] [考研] [Google Scholar][Ref list]

https://journals.sagepub.com/doi/10.2203/dose-response.003.03.004?icid=int.sj-full-text.similar-articles.4

asked same question about PFOS/PFAS and hormesis, SCROLL TO BOTTOM

[i finally craeted chatgpt folders after this so maybe I won’t say “scroll to bottom” as much from now on out]

A study integrated data from an exposome-wide association study and GWAS study on brain matter aging. They found that a number of environmental factors such as current tobacco smoking, length of mobile phone use, use of UV protection, and frequency of solarium/sunlamp were associated with brain matter aging. Several single nucleotide polymorphisms (IP6K1, GMNC, OSTN, and SLC25A20) were significantly associated with the brain matter aging (Feng et al, 2024).

May 12-15 there will be a conference in DC