#499

Scroll to the top and follow the instructions in this thread. also review this thread DIY Rapamycin Toothpaste and Flossing Paste

#500

Thanks so much for this post! I realize it is a few years old now but still great! Can someone help me with the math? I am trying to figure the percentage of rapa in this mix. If I ounce equals 28350 mg. how would you figure the rapa percentage?
If you convert 1.7 oz. to mg .you get 48195 mg.
So do you divide the 6 mg of rapa by 48195 to get 0.0001244942?
That doesnt sound right. what am i doing wrong? Can someone help me? Thanks!

#501

I would go with a simple illustration for this so we can see what some easy to do percent of the big number (48195) is :slight_smile: That helps to understand where you are trying to get to and is a Test of ones thought process.

Test
10% of 48,195 = 4819.5
1% = 482mg (rounded up)
0.1% = 48mg
0.01% = 4.8mg

So it looks like 6 will be closer to 0.01%

In this case I’d first add the 2 together as that will be the whole;
48195 + 6 = 48201 total weight
Then divide 6 by 48201 = 0.000124
To get percent multiply 0.000124 x 100 = 0.0124% - this is the step you were missing

The test above, indicates this is the correct percent.

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#502

Thank you so much Steve! I appreciate that.

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#503

Did you end up applying the lotion once or twice a day? I just made up some but instead of 6 mg like you I used 10. Mixed that with a little trans cutal and then mixed that with 1.7 oz of Neutrogena hydro boost water cream. I just don’t remember if folks are applying it once a day or twice a day. I just got my before pictures taken and can’t wait to take after pictures in a few months!

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#504

In the original study they did once every day or every two days… Rapamycin May Slow Skin Aging (Drexel U. Study)

I generally used it in the evening when I went to bed, when I was using it.

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#505

I take the Rap. Liquid I wonder if I could apply this directly to my face?

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#506

Interesting! I dont have an answer to your question but may I ask where you get the rapa liquid?

#507

my dr prescribes for me b/c I cannot take pills well. I get it at my local pharmacy I take 5 ml.

#508

what is the recipe for the face cream ? Im confused and want to try to make it !

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#509

If you scroll up to the top post of this thread there is a recipe for lotion but basically you crush up your rapa pills really well then you add the smallest amount of transcutol you can and mix it with the pills. I crushed up 6 pills and used 1/2 of a teaspoon of transcutol to mix with them. Then a think I added a touch more, a bit less than the 1/2 teaspoon the second time. The object is to try and not make your lotion any runnier than you need to. But you do need the transcutol for some reason (not just water) and someone on here can explain why better than i can, lol I let my pills sit in the transcutol for about 10 minutes or so, not sure if you even need to but i wanted to make sure they were really dissolved so my lotion didnt feel gritty. After the 10 minutes you mix your transcutol and pill mixture into your lotion. You can use any kind of lotion you like, i used Neutrogena Hydroboost water cream. I think it was a 1.7 oz. jar. I used a little hand mixer like in the recipe above. You want to mix it really well. i set a timer for 10 minutes and mixed away until the timer went off. Wala! You have rapa lotion. I put it on my face, neck hands and lower arms every night before bed. I took a bunch of before pics and will check every month with new pics to look any progress. Next time I think I will use up my Cerave Ve lotion just because I have it here already. Good luck!
Oh, and one more thing, if you scroll up just a little bit until you find @Steve_Combi 's post about how to figure the strength of your lotion as a percentage and follow his instructions he makes it soooo easy. it was a huge help to me!

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#510

There is no try, there is only do :slight_smile:

@Pupcuts has provided the info to help you get started. Lots of good info in this thread by many who have done this.

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#511

If some one could post some thing they tried with success ? There are a lot of versions ect ? Does any one have a basic recipe they used and liked ?

#512

what is tanscoutol ?

#513

since I use the liquid Rapa. Im wondering if I could just use this to mix in with some other lotion like Neurogena orCerave put a few drops into the over the counter cream and mix it ?

#514

I have never used rapamycin liquid so I am not sure. See if anyone else have. What is the strength of the liquid?

#515

Oh hey now, thats a thought (mixing your prescription lotion). I also would like to know the strength of your lotion? I wonder if the makers of your lotion used something like transcutol , They would have to use something to make their lotion so i also wonder if you could just add it to a neutrogena lotion .What is the reason for wanting to do this/ To make it go further? It will lessen the dose if you dilute it with another lotion.
As for wanting to see others results…I just started and took lots of pics so i could compare but Im not there yet. There was a study done, I think by the Drexel U with rapa that was pretty eye opening. Let me find it and i will share it with you here.
As to your question about transcutol. It is some kind of stuff you need to mix your rapa with once you crush up the pills to make it (I hope this the right word) soluble. I know it is necessary and i know it does something to your crushed pills to make them work or maybe mix better into your lotion. It also goes by other names. I got my at lotioncrafters.com . I dont know if you need it since you already have a prescription lotion you are looking to dilute with an OTC lotion. Maybe someone with more knowledge abour transcutol can pop in and share.

#516

do you think I could mix the liquid Rapa in to a carrier lotion and that would work? As mentioned the Rapa I use is a liquid- so Im wondering if I just use drops of the liquid Rapa. in some basic neutral face lotion …

#517

or maybe I could just literally use the liquid Rapa. on my face as it is- and my reasons are wrinkles / creepy skin

#518

Here is a little short vid about the rapa lotion. You can also go on Youtube and search rapamycin or sirolimus and get LOTS of good info about what it does for the skin. Have fun!