#245

Q: What would your 100th day of your life look like, and how would you like to spend it as you step out of bed in the morning?

Well, I step out of my bed these days and sit down in my wheel chair, so I am paying some price for old age, but I prefer it to being dead, and whenever I feel sad in a wheelchair, I think well you know Roosevelt ran the whole damn country for 12 years in a wheelchair. So, I am just trying to make this wheelchair thing last as long as Roosevelt did. - Charlie Munger.

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#246

For brilliant investors, Buffet and Munger have not been very smart regarding their health. If I were them, I would have dropped a couple of million a year on a good team of doctors to figure out how to help them live healthier and longer. The fact that they’re billionaires and not doing that speaks volumes to me. It’s obviously too late for Munger, but 99 is a good long life.

Munger didn’t care for grueling fitness regimes or punishing diets. Munger was a fan of donuts (in moderation), peanut brittle, and Diet Coke, and he avoided exercise as best he could, he said. He used a wheelchair in his later years but was mentally sharp when he died, the Associated Press reported.29 Nov 2023

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#247

It is also about life style changes and these guys are not going to do that.

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#248

It makes me think that it’s good for me because I feel good, look good, have very good skin, no wrinkles, no varicose veins, no pain anywhere, have all blood markers within norm, have normal weight, have great colonoscopy results, don’t have arthritis, and have very active lifestyle. Plant based diet makes me look and feel 20 years younger.

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#249

In all likelihood, everything you listed (benefits and state of wellbeing) is because of RAPA you been taking for years, and probably not related to diet. If i’m not mistaken you been taking rapa for over ten years, you cant ignore that.

#250

It is related to diet. I became a vegetarian at 16-17. At 50 (before Rapa) I looked 30 the most. Rapa probably helped later, but I’m not 100% sure about it.

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#251

I’m definitely not going to diss all carbs, because there is obviously healthy ones(especially for some people more than others) and I myself can’t go more than literally 7 days without eating carbs, but for most people (and a great majority of carbs such as ones found on grains and sugar and legumes) are really bad. Obviously, you are very health conscious and doubt you go to Dunken donuts every morning to get your 1/2 dozen donuts/carb fix lol.

Generally speaking, if i were to advise someone that knows nothing about food, I’d definitely tell them to stay away from carbs and stick with healthy fats and proteins for 80-90% of their daily needs. Carbs you really have to know if they sit well or not with you. I’ve mentioned before that if I eat legumes for three days in raw my whole-body swells especially joints. Do you think i give a damn what a science paper or a study or a doctor says of how good and healthy legumes are if i know for sure they are bad for me and make me sick. By same telling you NEVER hear cases where healthy fats or protein has such a negative effect on a human being despite the fact that you may or may not like meat/protein. As an example, the crapolla that somehow red meat is bad for heart is all but been destroyed by doctors themselves in last five years or so. It was all smoke and mirrors.

so long story short there is a wide ranging spectrum of foods that are good and healthy and for those that are very health conscious they can easily find a diet that works well for them, but for a wide array of people that have no clue about food and nutrition I’d definitely advise them to stick with meats and healthy fats and avoid carbs for the most part (except veggies and non-sugary fruits).

#252

Last thing I would want to do is argue with you, or be rude to you in any way, but I cannot stay without mentioning the fact that you did need to have an organ transplant, didn’t you? Now, I don’t know the history behind it (you definitely don’t need to tell it) but for an outsider who is at war with carbs (most of them not all) it raises doubt that your vegan diet might have not been the best viable option for you. just thinking out loud and also being religiously against cards. Btw there is literally more than 10 podcast from antiaging and healthy aging docs in you tube (in last week alone) and some of them very famous dudes saying exactly this, carbs are literally number one cause of all the health condition in our society today. As i said earlier some people do it the smart way, but for most people we need to scare the hell out of them, so they stay away from that poison.

Sugar Cravings, Red Meat, and Your Health | Max Lugavere | EP 456 (youtube.com)

THE BIOHACKING EXPERT: NEW Research On How To Live Past 100 Years Old | Dave Asprey (youtube.com)

Carbohydrates are NOT essential (youtube.com)

:red_circle: “I Ate ONLY ONE Food And My Parkinson’s REVERSED!” | Mimi Morgan (youtube.com)

#253

Carbs are not the number one cause of all the health conditions today. The problem is refined carbs, just like processed meat or unhealthy fats, and too many calories.

It’s just as wrong to blame everything on fat. If you stop eating carbs you are losing a lot of health benefits from whole sources.

If you think eliminating carb consumption is going to give you health benefits (1) it’s not going to do so (2) you’re going to quit that diet anyway, sooner or later.

This is a scientific site. If you have problems with science or citing scientific studies then you are on the wrong place, maybe some carnivore site would be better where you can share your anecdotes and speculations.

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#254

Yes, I’m convinced that eliminating carbs for a certain period and then introduce only healthy ones/carbs should yield amazing results. I also happen to believe that eliminating all food for up to 10 days (fasting) would result in very healthy outcomes. Again, many docs are saying this, it is not just me, so it is not totally anecdotal, it is science also. But IMO the main culprit (of health issues) is the overeating and not necessarily any food category. Some people will do fine in mainly carb diets, others in mainly protein and fats.

#255

I think the key might actually be personalized nutrition. Humans are omnivores but that doesn’t mean everyone needs to eat the same way. We can obviously survive on about anything but to thrive on an individual level the optimal diet is going to be a bit different for each person. It’s good to hear what others eat to get ideas but ultimately we have to try different things and approaches for ourselves to see what works for us. I know for myself that different diets (from vegan to carnivore) have worked for me at different times. Right now for me a mundane but highly satiating diet of minimally processed foods is giving me better results (labs and subjectively) than anything else I’ve tried so I’m just going to stick with that until I feel like it’s no longer working. Our modern food environment is very confusing and ultra processed foods are designed to be addictive so it’s no wonder people who switch to a diets that eliminate most UPF’s feel better.

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#256

I’m not arguing at all, nor am I advocating for it. Just sharing my story. My diet of plants (as carbs) is good for me. In fact I have no idea if it would be good for you or anybody else.

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#258

@SNK , Anuser is right in this statement. I really want to keep this site focused on real scientific information where possible, and that means the actual research studies listed in Pubmed.gov

Quoting Dave Asprey doesn’t really cut it here. He’s an MBA out of Wharton who sells coffee with butter in it as “health food” - and has made millions $, but he’s not a source for scientific information (or, I would argue ANY health information). And yes, Jordan Peterson even less valid as a source for scientific information in health.

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#259

-I guess I’ll have to agree with you on Asprey dude. Never checked much on him, but in last couple days been watching him a bit, and he doesn’t quite cut it for me either.

  • As for Peterson dude, I would not dare discount what he says in any subject man. He tends to do a LOT of homework before he speaks and when he does speak it would be very smart of anyone to listen to him, as his foes have found out (one, being the “humankind” not “mankind” PM of Canada LOL).
    Your point on science is well taken, but it tends to be fun to dabble once in a while on anecdotal and personal opinions also.
    Will try to keep it at a moderate/manageable level though. :joy::joy:
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#260

‘So what is a person looking to eat healthily supposed to do? “I think what it says is you should feel liberated to try a bunch of different diets and find one that works for you,” Pontzer says. But “when somebody tells you that there’s only one way to eat, they are wrong, and you can stop ­listening.”’

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#263

Its a little confusing how they’ve structured it below - but what they are saying is that foods (like cheese, dark chocolate, etc.) that are associated with a negative causal association with DMGA (GrimAge acceleration) are more likely to be contributing to a delaying of aging.

Causal benefits of 25 dietary intakes on epigenetic ageing: a Mendelian randomisation study

DNA methylation GrimAge acceleration (DMGA) and intrinsic epigenetic age acceleration (IEAA) are important physiological markers for assessing the ageing process. Evidence from cross-sectional studies suggests that some dietary intake is associated with DMGA and IEAA. However, the causal relationship between them has yet to be elucidated. This Mendelian randomisation study uses genetic variants associated with different dietary intakes as instrumental variables to explore the causal benefits of multiple dietary intakes on DMGA and IEAA.

Cheese intake, dark chocolate intake, average weekly red wine intake, dried fruit intake, fresh fruit intake, porridge intake, cereal intake, and liver intake had a negative causal association with DMGA, and poultry intake and doughnut intake had a positive causal association with DMGA (p < 0.05).

Muesli and bran cereal intake had a negative causal association with IEAA, and pineapple intake had a positive causal association with IEAA (p < 0.05).

Dietary intake positively causally associated with IEAA or DMGA may have accelerated biological ageing; conversely, dietary intake negatively causally associated with IEAA or DMGA may have contributed to delaying biological ageing.

Based on genetic evidence, this study demonstrated some significant causal benefits of dietary intake on DMGA and IEAA, suggesting the possibility of intervening in DNA methylation acceleration and epigenetic age acceleration by adjusting these food intakes, thereby promoting health and delaying ageing. However, the findings of this study are exploratory and preliminary and need to be supported and validated by evidence from further clinical studies and mechanistic studies.

Paywalled Paper: (please post paper if you can get it, it might be interesting to read).

https://www.tandfonline.com/doi/full/10.1080/09637486.2024.2379817

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#264

Agree, @Virilius! I would even say, it is only possible with enough carbs.

I agree that on cardio and resting days, carbs can be applied sparingly. However, for those aiming to build and MAINTAIN muscle, it’s crucial to provide the body with proper growth stimuli and not follow a “spare flame” nutrition pattern on weight lifting days. Without enough glycogen, you risk burning muscle through gluconeogenesis.

Balancing weight lifting with cardio requires careful carbohydrate management. On weight lifting days, I am introducing slow-digesting carbs to ensure a steady energy supply and maximize growth stimuli. Insulin and IGF-1 are critical post-workout, helping transport glucose and amino acids into muscle cells, promoting repair and hypertrophy.

→ Proper carbs nutrition supports the anabolic effects and prevents muscle breakdown trough gluconeogenesis.

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#265

Dave Asprey gave a lot of credibility to biohacking when there wasn’t really any, just like Sinclair he is a hero of sorts.

#266

Breakdown of the effects of major diets

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Digesting the complex metabolic effects of diet on the host and microbiome

https://www.cell.com/cell/fulltext/S0092-8674(24)00706-2

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#267

Dave Asprey may have given a lot of attention to the field of biohacking, but he’s a quack that decreases the reputation of the field.

As for Jordan Peterson, he is super smart and knowledgeable on a lot of subjects but diet is not one of his subjects of expertise. Strict carnivore diet works as an elimination diet that can be beneficial for people that have some weird health problems caused by intolerances to a wide range of foods. Just because carnivore helps such people doesn’t mean it is generally healthy, just like avoiding eating peanuts isn’t generally healthy just becuase some people have a peanut allergy.

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