The immune system is pretty amazing and with a few tweaks can be even more amazing.

Cancer sucks but it looks like this specific one can now be treated effectively,

PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer

Results

A total of 12 patients have completed treatment with dostarlimab and have undergone at least 6 months of follow-up. All 12 patients (100%; 95% confidence interval, 74 to 100) had a clinical complete response, with no evidence of tumor on magnetic resonance imaging, 18F-fluorodeoxyglucose–positron-emission tomography, endoscopic evaluation, digital rectal examination, or biopsy. At the time of this report, no patients had received chemoradiotherapy or undergone surgery, and no cases of progression or recurrence had been reported during follow-up (range, 6 to 25 months). No adverse events of grade 3 or higher have been reported.

https://www.nejm.org/doi/full/10.1056/NEJMoa2201445

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