Indeed it is. I also tend to watch/listen at 1.5-2 times the speed, albeit at moments I have to get back as the audio sounds garbled like chipmunks.

BRYAN JOHNSON IS A BUBBLE WAITING TO BURST, but that might be a good thing. I’ve been reading the book “Bubbles and the End of Stagnation,” which argues that many scientific and technological breakthrough’s of the last century (the Manhattan project, the Apollo mission, bitcoin, dot com explosion and implosion) were speculative bubbles, where over-investment and societal enthusiasm led to transformative advancements that would not have otherwise occurred. This view turns the typical narrative of bubbles as a negative phenomena on its head, instead positing that they play a crucial role in driving progress.

One sentence book summary: yes, each bubble may burst and many will lose a lot, but the progress made during the bubble will be left behind, and that progress would not have been possible without such crazed zeal.

I think that @bryan_johnson is, wittingly or unwittingly, creating just such a speculative bubble with his Don’t Die movement, which fulfills all the properties of bubbles that Hobart and Huber identify in their book:

1/Self-fulfilling prophecy (i.e. reality distortion field): Johnson’s claims are audacious—like the possibility of halting or reversing aging— yet they promote a reality where such ideas gain credibility and resources. By presenting his vision as inevitable, he helps to reshape societal expectations, which, in the best case, pulls forward investment and innovation in longevity.

2/FOMO & YOLO: If you don’t buy in to Don’t Die you will die, so don’t miss out. And you only live once, so don’t die.

3/Excessive risk taking and over-investment: Its hard to find something that Bryan does that isn’t risky and expensive; complete plasma replacement, 100+ pills a day, spending $2mil/year, follistatin gene therapy.

4/Definite optimism: “By following the blueprint plan [definite] I, and you, can live forever [optimism]”.

5/Strong social interactions between motivated and capable individuals: Don’t Die meetups, his social media presence, etc.

The bull case: Bryan Johnson’s narrative of “if you survive until year X, technology and AI will be so advanced as to make you live forever” will set off a self-fulfilling process. This narrative will shift societal priorities and accelerate the demand for life extension technologies, which will in turn lead to the investment and research necessary to make his claim’s possible.

The bear case: unfounded claims will inevitably go unsupported, tearing to shreds what little credibility the longevity field might’ve had, and putting us into a longevity dark age. In the process people will get hurt copying his “treatments.”

So, which future timeline are we on? I honestly can’t make up my mind. I don’t think we’ll all live forever, but I do kinda think that the Don’t Die hype might do net good.

What I know for sure is that the response I get when I tell people I do aging and longevity research has substantially changed in the last couple of years. I used to get blank stares, now I get “oh, like that millionaire on twitter with a blood boy?”. To me, it feels like the narrative fly-wheel is already spinning, the bubble is already forming, and something is going to happen.

https://x.com/ZaneKoch6/status/1869193857235370378

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That’s an impressively badly reasoned article.

Who is more likely to run into trouble in the next five years? Byran Johnson, with a team of medical professionals constantly monitoring him, or some random schmuck who reads something on rapamycin.news and (due to Dunning Kruger effect ofc) unintentiionally nukes himself?

There is no such thing as a bubble before it has happened.

… "People see bubbles where there are none,” Fama told the group, in an appearance that was live-streamed.

To bolster his point, Fama cited a celebrated experiment in a faculty lounge at Stanford. A bunch of professors were presented with charts of agricultural prices. Their charge was to identify any bubbles. The profs did so, and then learned that the data were randomly generated. No patterns existed.

Bubbles are apparent only after the fact, Fama contended. “The way I interpret it is: You must be able to predict the end of it,” he said. “A bubble has to be something with a predictable ending.” And he added: “What’s the testable proposition?” …

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At the end of the day, I don’t care what anyone’s opinion of Bryan Johnson is. I am only interested in the protocols he is doing and what his results are from them to see if I can learn something from it.

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Good trailer, not much traction yet (94K views).

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Just wondering a few things about Bryan Johnson’s protocol. Baby Aspirin 3X a week? Why? Metformin does seems very high, he eats clean?

Bryan Johnson recently stopped Rapamycin and posted on X/Twtter about it:

https://x.com/bryan_johnson/status/1857131261980270933

From his recent blog on BluePrint: In September I stopped Rapamycin, based on concerns around its metabolic side-effects observed in my lab results (including increased cholesterol, blood sugar and RHR); the data here showed Rapamycin increased biological aging according to two clocks, while ineffective according to the others.

Thoughts on this?

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Welcome to the forum!
There’s a long thread about this here:

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Hello!

I have a commercial design background. A lot of Showmanship with Bryan J.

I think he blew off rapamycin without good reasoning. But, fine for him.

By biological age based on glycans and methylation is 15 to 20 years better. Pretty sure it is the rapamycin for 4 years.

Welcome to the dialog.

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a more ambitious film would recognize this material, foremost, as a story of familial estrangement and religious seeking, and more fully integrate these elements into its narrative DNA. For all its anti-aging trappings, Smith’s movie is most intriguing when detailing Johnson’s crippling depression at the height of his professional success, his decision to leave the Mormon church, his ongoing estrangement from two other children, and other personal stories.

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:crown:

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Is the documentary any good? Does it actually discuss his protocols or is it more or less just about his life and how we got to where he is now?

I am a little more interested in the protocols than a biography, but that’s just me

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I think it was more about his mission and life, and less about his protocols.

Those are mentioned, but there is nothing in there you don’t already know if you’ve followed him at all. I really like the guy and I fast forwarded through some sections if that tells you anything.

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I saw it yesterday. It is his very personal story and more about himself, his background and his “movement” than deep diving in the protocol. But I found it interesting to learn about his story, as he presents it. So no, not much about his protocol. It is aiming at the public, not at avid biohackers or health optimizers. The general audience does not know what red yeast rice is or what lutein is. It would not be relevant for most viewers if they started to dive deep into specific supplements. It does not mention specific supplements but Rapamycin is mentioned once.

Yes, he sells supplements, and some might hold that against him. I don’t. He is an entrepreneur going all in on longevity. He puts his name on a line of supplements. A supplement industry where fraud is a big part of the game. The industry needs players that are honest and actually sell what is stated on the label of the bottles, full disclosure, third party testing and scientifically-backed dosages. I don’t buy the blueprint line of wellness products. I create my own regimen of supplements from brands that I trust.

But I think he is one of the good guys in the industry.

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He did quite well with the concept of a black swan, but actually there are black swans in Australia and a town in Devon keeps them as well (Dawlish).

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I also genuinely think he’s a good guy, so I may watch it anyway at some point.

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As long as you know what to expect, I think you’ll enjoy it. I don’t regret the time spent.

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I agree, The cynics think it is only about $$ but no business person in their right mind would spend the money he has to insure product purity. I don’t think he is making money at this at the moment

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Yes - I do agree with that. I do trust his products more than most supplement companies. His credibility would be destroyed if they didn’t test (e.g. via consumerlab.com) to be good products with the content claimed.

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