Allostatic load/stress and metabolism. Stress and Growth, maintenance, and repair (GMR) processes decrease

AlexKChen · 2025-02-10T15:51:30.559Z

The energetic cost of allostasis and allostatic load

Chronic psychosocial stress increases disease risk and mortality, but the underlying mechanisms remain largely unclear. Here we outline an energy-based model for the transduction of chronic stress into disease over time. The energetic model of ...

Also see why zebras don’t get ulcers

Other studies, although not all (Lindqvist et al., 2018; Picard et al., 2018b), have reported elevated numbers of mitochondrial DNA copies per cell (mtDNAcn, (Picard, 2021)) in the blood of individuals with early adversity and psychopathology