Big thanks! Let’s see what other interventions that may come up instead of cryo but I’m open to many things as long as they can be proved to be safe and work. Full body replacement is also one interesting potential intervention but before that intervention gets well-developed I don’t think I will be alive. Do you have any intervention that you keep an extra eye on?
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Personally I have never really been that enthusiastic about cryo. It may be possible to modify the human metabolism to move in the direction of a form of temporary hibernation, but going through the freezing point of water looks to be too much of a challenge.
Are there any other cutting-edge intervention that you think is more promising? I see cryo as plan B if plan A fails and no cutting-edge intervention are discovered or enough well-developed when I need it.
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As I have said I think the main mechanism(s) that causes aging are about mitochondrial inefficiency (caused by heteroplasmy in the main) and partially associated acetyl-CoA levels. I also think there are a number of interventions to improve this which is what I am working on.
I cannot myself think it worth going through the cryo process. I don’t think it would be like going to sleep and waking up feeling refreshed. I am not myself sure I would wish to undergo such a process.
As far as I am personally concerned with the interventions I have used over the past few years I have substantially improved my quality of life. I intend to keep going with this approach.
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Neo
#7
Is this approach in the category of adding 5, 10, 15 extra years or do you think it can be a game changer beyond that?
Neo
#8
There is a spectrum here
For instance giving you your young bone marrow when you are 50 and new kidneys when you are 60 is perhaps not that far fetched
Those two combined could help give you a bride to further improvements
You might like this thread
https://spotify.localizer.co/t/regenerative-medicine-growing-new-organs-etc/12486?u=neo
Neo
#9
Btw
You’re on an airplane when you hear a loud sound and things start violently shaking. A minute later, the captain comes on the speaker and says:
There’s been an explosion in the engine, and the plane is going to crash in 15 minutes. There’s no chance of survival. There is a potential way out—the plane happens to be transferring a shipment of parachutes, and anyone who would like to use one to escape the plane may do so. But I must warn you—the parachutes are experimental and completely untested, with no guarantee to work. We also have no idea what the terrain will be like down below. Please line up in the aisle if you’d like a parachute, and the flight attendants will give you one, show you how to use it and usher you to the emergency exit where you can jump. Those who choose not to take that option, please remain in your seat—this will be over soon, and you will feel no pain.
What would you do?
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These are difficult questions to answer. I think it can be a game changer in dealing with the health issues caused by those mechanisms.
I would be one for trying the uncertain.
I think I will have faith in cryo on the day someone is revived and restored. Until then, cryo is just an expensive grave.
IMO it has a real danger of almost working. Hence something is revived, but not something you would ever wish to be.
Right now, as far as I know, no human has been restored. And, no animal has been restored after more than a day or so. (I don’t count tardigrades)
The theory is that if frozen a creature may be restored some time in the future and whilst being frozen no changes occur. However, apart from the fact that there is relatively little security in being kept frozen, it strikes me that so much damage occurs in the process of being frozen that it would be unlikely that anyone would wish to come out of the process in an sentient state.
It may be that we can work out how to hibernate. Going beyond that, however, strikes me as really difficult.
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Neo
#16
How about you Chris, what would you do above?
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ng0rge
#17
It would be a cold day in hell that I would consider cryopreservation, and I mean really cold! At this point, I’m very concerned about what the state of the world will be in 5 years - I’m going to live for today…and hope for tomorrow. Cold therapy, maybe, but I’m not jumping into any freezer that I can’t jump out of.
And @Neo given any option other than certain death is a no-brainer…I’ll jump out of the plane with just a parasol.
Neo
#18
Yes, it’s a bit like this:
Does one take the leap?
You, @DeStrider , @ng0rge and others might find this interesting.
It was one of the more fascinating reads in a while - so if nothing else you might find it very interesting.
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In that case I’d use the parachute. Cryonics is like adding that you must donate your financial assets not to your family but to the parachute company no matter what happens.
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ng0rge
#20
I just skimmed through it…probably more than I wanted to know about cryonics (I thought it was more like suspended animation). And the question about when you are actually dead is troubling. “he’s dead, Jim” “Dammit Jim, I’m a doctor…not a corpse revivor!”
The technology that I think is more practical and not unlikely if I live 30 more years, is this (from the article you posted). “a hypothetical future technology called “whole brain emulation,” where an entire brain structure can be uploaded to a computer with such perfect accuracy that everything about the person is intact and alive in a virtual world.”
The thoughts and personality in my brain are what matter. At my age, I could use a better body. And I’m a little nervous about freezing my head - I’m afraid that @AnUser might get ahold of it.
P.S. Cryonics also reminds me of one of my favorite movies…" They Saved Hitler’s Brain" so I wouldn’t want my head to end up in the freezer next to his.
https://www.imdb.com/title/tt0265870/?ref_=nv_sr_srsg_0_tt_8_nm_0_q_saved%2520hitler
Another approach (in the PDF below you can zoom in to read the small text if you want):
Source: https://x.com/turchin/status/1764991259960054083?s=20
IMMORTEN2.pdf (104.8 KB)
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Neo
#22
Interesting- do you think any “upload” is you or a copy of you?
