1,4 -DPCA breakthrough Drug For Tissue regeneration

Paul_2.0 · 2023-12-07T01:35:36.626Z

This sounds like a really interesting molecule, has anybody heard of it?

The Journey of 1,4-DPCA: A Promising Drug for Tissue Regeneration

Learn about 1,4-DPCA, a promising drug that activates regenerative responses in mice and rats, with the potential to revolutionize regenerative medicine. Discover the breakthrough in healing and the future of 1,4-DPCA.

Est. reading time: 2 minutes

RapAdmin · 2023-12-13T02:57:13.693Z

Heber-Katz has patented the use of 1,4-DPCA for tissue regeneration and co-founded MRL Bio, a company dedicated to translating their laboratory successes into real-world applications. Despite skepticism from some biologists about the complexity of true regeneration in mammals, Heber-Katz remains optimistic, emphasizing the drug’s ability to promote the growth of healthy new cells. The next steps involve testing the drug in larger animals, with eventual aspirations for human studies.

Chemical & Engineering News

Small Molecule Triggers Tissue Renewal

Regenerative Medicine: Compound boosts levels of key protein, helping mice to regrow healthy tissue cut from their ears

medicalxpress.com

Regenerative drug restores bone in preclinical study

Bone loss is a part of aging that compromises quality of life and movement in many older people, but regenerative treatments to improve their health and well-being have been limited. Now, a study led by Lankenau Institute for Medical Research (LIMR)...

PubMed

An injectable hydrogel-formulated inhibitor of prolyl-4-hydroxylase promotes...

The hypoxia-inducible factor 1α (HIF-1α) is critically involved in tissue regeneration. Hence, the pharmacological prevention of HIF-1α degradation by prolyl hydroxylase (PHD) under normoxic conditions is emerging as a promising option in...

https://www.inquirer.com

Regrowing nerves and healing without scars? A Main Line Health scientist’s...

An accidental discovery in 1996 launched Ellen Heber-Katz on the quest for the secret of regeneration.

Frontiers

Prolyl-hydroxylase inhibitor-induced regeneration of alveolar bone and soft...

Bone injuries and fractures reliably heal through a process of regeneration with restoration to original structure and function when the gap between adjacent sides of a fracture site is small. However, when there is significant volumetric loss of...

Paul_2.0 · 2023-12-13T03:41:34.195Z

This is great. Sounds like it has a lot of applications. I’m guessing it’s going to have to be localized for wound healing. It may end up having cosmetic applications for scarless surgeries. Amazing.