Yet all cause mortality is lower amongst people who take statins than in those who don’t.
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KarlT
#22
I’m no sure what Dr Greene meant by “silent”, but it is fairly standard for anyone started on a statin to have liver function tests done at 3 months and yearly.
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Of course I would stop taking cholesterol meds if I could figure out how to get my apoB to <60 without the meds. Haven’t figured it out yet.
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But what about this observational study with 21 participants where a keto scientist showed that using statins correlates with cancer at the age of 114? This clearly disproves decades of intervention study results with millions of participants.
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AnUser
#26
Lmao the meme was too offensive… I guess people can’t take a joke.
AnUser
#27
I wasn’t started on a statin, I just ordered it myself online. That’s why I was interested in what tests to do. The medical system is murderous in many countries, completely ignoring longer risks than 10 years. It’s impossible to get prescription in many places for statins unless one’s LDL is above the 95th percentile when below a certain age. David Sinclair had to forcefully convince his doctor to start him on a statin in his 20’s. He’s doing quite well with no problems with his heart despite terrible family history.
KarlT
#28
Hopefully, you have a health care provider of some sort that knows you’re on a statin, or at least could check a standard Liver function panel.
Always good for those of us trying these interventions to have an objective observer following us.
You may not be a doctor, but the famous saying applies: A physician who treats himself has a fool for a patient. Not a criticism, but advice to be careful.
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AnUser
#29
I can order liver tests, I will do that, thanks. I will also be checking my apoB. So far I feel good on statins. I always looked forward to taking them, placebo is hell of a drug. I’ll use a CGM later on for blood sugar - I’m not worried about type 2 diabetes, I think that can be reversed in all cases.
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DrRoss
#30
Regarding the use of ANY statin…it is critically important to supplement with CRYSTAL-FREE COENZYME Q10. Statins work by blocking an enzyme in the liver named HMG-CoA (hydroxymethylglutaryl-coenzyme A) reductase. HMG-CoA is the rate-limiting enzyme in the cholesterol biosynthesis pathway. BUT…by blocking HMG-CoA, YOU ALSO BLOCK THE BODY’S ABILITY TO SYNTHESIZE COENZYME Q10.
The melting point of CoQ10 is 10 degrees higher than body temperature, which causes the CoQ10 to crystallize, We cannot absorb ‘clumps’ of CoQ10, it must be single molecules in solution. I take & recommend brand of CoQ10 made by Pharma Nord (Denmark). They have a patented method that keeps their CoQ10 in solution (tested & proven).
Here is link to my article on crystal-free CoQ10:
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AnUser
#32
Yes, because of Brad Stanfield’s video, I don’t believe I have to take CoQ10.
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There is absolutely NO valid evidence that you need to take CoQ10 if you take a statin.
But, if you want to it won’t hurt you.
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bcmd
#34
Statins can indeed increase insulin resistance/DM2 over time. May be dose/duration and specific statin-related. Considering that’s as big or bigger of a problem than high apob/ldl it’s something to really consider and monitor.
Ezetimibe may be a better first line drug and may even reduce insulin resistance. Perhaps pcsk9 inhibitors as well but those can be pretty pricy and there’s some unclear murmuring evidence around increasing insulin resistance.
The best overall “drug” for cholesterol is probably bioidentical estradiol for both women and men. It’s the loss of estradiol after menopause that causes the large spike in cv risk for women. Men with high testosterone levels have high estradiol levels as well due to aromatization which is cv protective. Men put on optimized levels of bioidentical testosterone can even take extra supplemental estradiol and it reduces apob/ldl, increases hdl, and even reduces lp(a) without causing any feminizing effects.
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nym
#35
my AST went up after being on 10mg rosuvastatin for not even 4 weeks. also developed extreme thirst and noticed my serum creatinine went up.
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Jonas
#36
what is the best ARB in your view? Losartain (Peter Diamandis) and Telmisartan (Bill Boon)? TIA
If you haven’t tried Pantethine which should be available in most places I certainly would give it a shot. I am using it at a once a day in the morning, 600mg and it has lowered my LDL cholesterol to the lowest levels I have have ever had. If 600mg doesn’t do it for you, try 600 mg twice a day. I personally had zero side effects from 600 mg.
“Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation”
“Pantethine was reported to reduce total cholesterol levels and fatty acid synthesis and potentially alter different processes that might be involved in the SARS-CoV-2 replication cycle.”
https://www.tandfonline.com/doi/full/10.2147/VHRM.S57116
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AnUser
#38
You should probably be testing apoB by the way, as you can have a low LDL and higher apoB or vice versa. And apoB is more implicated than LDL. It looks somewhat interesting at first look, but it can’t replace a statin, most likely I’d use it in combination if I have to.
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Mostly there is a correlation between LDL-C levels, TG, HDL_C and non HDL-C and apoB levels.
@desertshores lipid panel looks 
I would estimate (with some good certainty) his apoB are between 40 and 50 mg/dl which makes him way better than 5th percentile for his age group. Sure he could test it, but there is really no need other than curiosity.
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How do you know it won’t replace a statin? That is exactly what I am doing. I will post the results of using Pantethine only after my next blood test.
I haven’t tested my ApoB lately. My last test was from Nov.2022 before I started Pantethine.
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Thanks for the tip. I’ve ordered some. I’d love to find the path to keeping low apob without a statin.
