#1

I have read the Pendulum’s research. Does anyone have a experience supplementing with Akkermansia over a period of time? What have you learned and what are the effects other than on BG?

#2

I’ve seen nothing showing that one can supplement directly with Akkermansia. Rather one has to supply the gut with the right nutrition/environment to promote the growth and sustainability of Akkermansia.

See discussions at: Immunity Code by Joel Greene and Akkermansia muciniphila, can strip the sugar coating from IgA antibodies, potentially leading to immune friendly fire.

Can you post “Pendulum’s research”?

Having a way to directly “supplement” with Akkermansia could prove very interesting.

Also, what do you mean by “BG”?

I just found Pendulum’s webpage on Pendulum Akkermansia.

Interesting, but it leaves me with questions:

  • Does their product have an enteric coating so that the “live Akkermansia” doesn’t get destroyed by stomach acid?

  • Does the product have some other means of delivering the Akkermansia to the gut?

  • How do they determine dosage?

OK, just saw that the webpage claims the product uses some kind of enteric capsule:

Akkermansia is encased in a plant-based, acid-resistant, delayed release capsule so that the strain gets through the stomach acid and to the gut microbiome where it can do its job.

Three months to really work seems like a lot.

Joel Greene’s microbiome protocols appear to resent a microbiome in weeks rather than months.

I remain interested but skeptical.

Has anyone used this stuff or any of their other products?

#3

You might both find this thread helpful

Would love to hear your thoughts once you have read it:

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#4

And you might both also like to read this

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#5

I’ve been using the Pendulum Glucose Control product for two months. I’m not using it for glucose control as I’m fine with my A1c/fasting blood glucose level. I’m trying it so see if I can get any benefits from its potential to strengthen gut lining/reduce gut permeability and increase butyrate production. Glucose Control contains multiple strains of bacteria, not just Akkermansia, so any perceived benefits I get may not be from that strain specifically.

Since I’ve started it I’ve experienced increased gut motility and a scaly, raised pink patch of skin on my forehead has faded significantly. These are associations, I’m not sure if there is any causation involved.

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#6

I used the Pendulum Akkermansia product for one month and noticed no improvements in anything.

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#7

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FYI. I’ve switched to the PRO products since they are on Fullscript. Fullscript is going to run a big sale (pendulum and more brands) in mid May. Message me if you want access. Anyone who has already set up an account will get notice of the sale.

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#8

My HBA1C went from 5.7 to 4.9 after using Pendulum Akkermansia and Polyphenols for a month as well as taking 500 mg Metformin daily. The benefits probably come from both actions, but it seems much larger than I would have gotten from Metformin alone. When I was prediabetic, I only took 1 g of Metformin weekly.

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#9

Have you switched to that product that contains 500 million AKK per capsule? Why not switch to GLP-1

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#10

I did switch to the GLP-1 product. My gut motility improved after about 2 weeks (back to how it felt with the Akkermansia only product before I stopped using the supplement due to cost). I haven’t checked HbA1c yet to see if I’m getting the same benefit as on just Akkermansia but I feel good.

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#11

Glad to see you mention their polyphenols. I’m taking their glucose control and taking one pill a day (just to keep costs reasonable). I chose that product after hearing Attia say good things about the company.

According to ZOE, I have a horrible gut, so this is my main interest for pro/pre-biotics

They just gifted me a bottle of their polyphenols and I had wondered if it’s worth purchasing in the future. Do you see value in that particular product and plan to continue?

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#12

I only took the product for a month. I also added 500 mg of Metformin daily.

Due to a miscalculation when I used a glucose calculator instead of a fasting glucose one (which provide very different numbers), my HBA1C was not 4.9 as I thought. It’s actually 5.4. So I went from 5.7 to 5.4.

Unfortunately, now I think the reduction was mostly the Metformin. However, I did buy another month’s supply of Akkermansia, so we’ll see what happens at the next blood draw in August.

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#13

Does anyone know where to get this delivered to Europe?

#14

I ordered 2 bottles once from supplements megastore and my order never arrived , nor did I get reimbursed, despite my claim. I am thinking of trying the akkermansia pasteurised ones since at least I can order from EU firms … iherb would send it to Eu too but every time I checked it was not in stock so I gave up.

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#15

I am trying akkermansia from codeage right now in hopes of increasing glp-1 but we’ll have to see. Nothing notable to report so far.