Yogurt consumption and risk of mortality from all causes, CVD and cancer: a comprehensive systematic review and dose–response meta-analysis of cohort studies

Summary: yogurt good for you

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Oh but you get satisfaction from denying yourself. I’m surprised you quit the CR which sounds like an endless source of pleasure from pain. I’m like that too but only with exercise.

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LOL, I quit CR for purely practical and social reasons :grin:. But it has had many permanent effects anyway. I automatically consider calories whenever confronted with food. Taste buds have been altered: I practically cannot enjoy almost any desserts, because they usually taste unbearably sweet… it’s a constant experience, where we buy some tempting looking dessert, cookies, chocolates, pastry whatnot, bring it home, take one bite, spit it out - inedible. Last night was an example, we brought some dark chocolate almond sea salt brittle from TJ’s. Had a piece after dinner as a treat, while watching a movie… couldn’t eat more than two bites - too sweet. Into the garbage it goes. Every week shopping trip, same story, “let’s try this one, looks tasty”, then, “too sweet”, garbage. Interestingly, when we travel in Europe, there are fewer of these problems, as the pastries over there are less sweet… but we’ve noticed that it’s changing and moving to packing it with more sugar as the trend to more sweet spreads all over the world and local recipes change. These days, it’s more Eastern Europe where the high sugar trend hasn’t penetrated much as yet, though alas it’s only a matter of time.

On a completely different note, that yoghurt study claims significant effects, which may be true, but the effect size is tiny, hardly worth making a fuss over. And btw. yoghurt is another thing that is being ruined with massive sugar, sigh. You always have to be super vigilant reading the labels, because the maniacal compulsion to stuff sugar into everything is relentless. I for one see no mystery why there is an obesity epidemic sweeping the world😢.

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My breakfast is pretty much the same besides I put everything in a blender and instead of granola use organic cooked quinoa. I also add 1 broccoli floret and a spoon of cacao and spirulina in addition to red beets leaves and stems. It’s an amazingly delicious mixture to energize for the day.

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Yes, you are right. It’s the reason that I make my own from 1% organic milk. Every morning I have a fresh batch. To make it I use different probiotic capsules.

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I take Siggi’s Icelandic skyr, plain, no fat. It has 19 g protein per serving for those interested in higher protein intake.

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全文:
https://www.science.org/doi/10.1126/science.ade7114

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Yes. The vast majority (if not all) of the polyps that I have had removed are from the left side of the colon or rectum. Thank goodness for colonoscopies!

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I made the mistake of buying a bag of dried blueberries at Costco. I figured a few in my oatmeal would be nice. The first bite was horribly sweet. Yuck. They coated the blueberries with even more sugar! Gotta read the labels.

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Tattoos as a risk factor for malignant lymphoma: a population-based case–control study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00228-1/fulltext

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Costco sells Wyman’s Wild Bluberies, a 4 lbs bag, frozen. Perfect for mixing with kefir/yogurt.

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Source: https://x.com/drkeithsiau/status/1897012486739779606

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Yes. Almost all of my polyps were found in the sigmoid/rectum area. It just reinforces that I’d probably be dead of colon cancer right now if they hadn’t been removed.

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The thing that’s a bit of a downer is the whole prep ritual. But the very newest thinking seems to be that modern colonoscopies can be performed with minimal or even no prep. If this really pans out with no worse quality, I think it would dramatically improve the frequency of patients willing to have a colonoscopy. You could have it every three years or even yearly depending on how many polyps they find. You wouldn’t dread the prep, which basically ruins 7-10 days of normal eating disrupting your life for two weeks. I can’t wait until no-prep colonoscopies become standard.

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Not sure what you are talking about. The prep for my colonoscopies started the night before, and the colonoscopy was done first thing in the morning. However, you do sit on the can for a while while your system is cleaning itself out!

Considering the alternative of colon cancer and death, a bowel prep every 2-3 years seems a small price to pay!

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Umm, not sure what you mean… everytime I’ve had a colonoscopy, I’ve gotten detailed prep instructions that upend your diet several days before and after. Certainly not just the night before, lol! This is at UCLA, but I think the same(?) at other providers:

Dietary Restrictions:

  • 2-3 days before: Avoid foods high in fiber, such as fruits, vegetables, whole grains, nuts, and seeds.
  • 1 day before: Stick to a clear liquid diet, which includes water, juice (without pulp), broth, and popsicles.
  • On the day of the procedure: Do not eat or drink anything after midnight.

This is just the diet - and the nurse that spoke to me recommended actually a five day prep before the colonoscopy, and then a whole week of recovery protocol after the procedure.

You also have to factor in all the medications too, stool softeners, the other meds (btw., Peter Attia spoke of these meds and how outrageously expensive they are!).

You are basically wrecking your microbiome and flushing it out - extremely invasive and hard on the system. It takes months and years to build up a good gut microbiome, so flushing it all out is a huge loss. Afterwards, you need restorative dietary therapy to regain your microbiome, which frankly can take months (does for me - I’m not back to normal for 2-3 months).

So at a minimum, you are looking at two solid weeks of utter disruption around the colonoscopy that affects not just your diet, bowel frequency (sudden loss of fiber is extremely disruptive to my digestive system as a very high fiber consumer), but also exercise, sleep and other activities of daily living. It’s also definitely high stress for those two weeks at a minimum, and a long recovery.

To get back to the point, I in turn don’t understand how you see the prep as trivial - to me, it’s self evidently a huge deal and a real challenge.

Of course we may be experiencing different protocols, as I only have personal experience with UCLA. YMMV.

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Hong Kong Hospitals have a much different protocol. Simply stop eating by 6 pm the night before and doing a colon cleanse where you poop everything out. The next morning they go in and look around and remove any polyps they find with little scissors on their scope. It sounds much easier than what you did. I’ve done 5 of these, and it’s the same protocol.

They do recommend no fiber or veggies after breakfast on the day before.

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The alarming rise of colorectal cancer diagnoses in people under 50 (New Scientist)

Colorectal cancers will soon be the number one cause of cancer death among people under 50. Could changes in lifestyle and environment be to blame?

From being virtually unheard of in the 20th century, early-onset colorectal cancer (EOCRC), as it is called in people under 50, now accounts for around 10 per cent of all new cases worldwide. That number is predicted to more than double by 2030, and by then, EOCRC is expected to be the most common form of fatal cancer in Americans aged 20 to 49.

The reason why is uncertain, but an ambitious new project is exploring potential causes – as well as the idea that EOCRC may be a distinct and more aggressive form of the disease. Meanwhile, as routine screening is extended to younger groups – in January, England lowered its screening age to 50 – and new, less-invasive tests get approved, there is hope the worst prognoses can be avoided.

Colorectal cancer is an umbrella term for cancers of the large intestine and rectum. In 2022, the year for which the most recent figures are available, there were around 1.9 million new diagnoses worldwide, making CRC the third most common cancer after those of the lung and female breast. More than 900,000 people died from it that same year, reflecting its lethality – despite advances in treatment, it kills around half of those who get it.

The growth is an illustration of what is known as the birth cohort effect, according to Marios Giannakis at Harvard Medical School. Each successive generation has a higher risk of developing the disease than older cohorts had at the same age. In the US, for example, people born in 1990 have roughly double the risk of developing colon cancer and quadruple the risk of developing rectal cancer throughout their lifetime as those born in 1950 (see graph).

For EOCRC, the birth cohort effect began in people born around 1960, supporting the idea that the rise might be related to changes in environmental exposures, says Giannakis. Additionally, though a significant portion of cases seem to involve a genetic contribution, the majority of recent ones are “sporadic”. These aren’t related to genetic predisposition, but rather are linked to lifestyle or environmental factors.

Potential triggers

But what factors exactly? From the 1950s, people in the parts of the world that have witnessed this rise experienced major changes in lifestyle that altered their environmental exposures, points out Manon Spaander, a gastrointestinal oncology researcher at Erasmus University Medical Center in Rotterdam, the Netherlands. People began consuming more highly processed, low-fibre foods, red meats and alcohol, while also sitting more and moving less. Alongside this came an increase in obesity and conditions such as type 2 diabetes.

At the same time, the use of antibiotics soared. Antibiotics can have a profound impact on the gut microbiome, and there is good evidence that disturbances to the microbiome are a risk factor for CRC at any age. So are inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease, which have also risen dramatically in young people, probably as a result of similar environmental changes.

All of these and more have been suggested as potential causes of the EOCRC surge. But despite years of research, “it’s not fully understood why rates are rising so rapidly in this age group”, says Bailey. The strongest evidence is that obesity, type 2 diabetes and high consumption of sugary drinks are risk factors, according to a recent review led by Natalie Cook at the University of Manchester, UK. But research on other potential triggers has produced conflicting results. For example, some findings show a link between heavy consumption of processed meat and EOCRC, but others don’t; similar research on red meat, alcohol, smoking, lack of physical activity, antibiotics and low intake of fruit, vegetables and fibre has also proven inconclusive.

Read the full article: The alarming rise of colorectal cancer diagnoses in people under 50 (New Scientist)

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I can tell you that no matter what I have done, it has not reduced the number of polyps I have. I have eaten less meat, more vegetables and fiber, oatmeal for breakfast, no alcohol, etc… I still have 2-3 polyps every 3 years.

There must be something that I can do to reduce the number of polyps, but I haven’t found it so far. The best thing has been removing them.

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From the different posts above, how are you doing with things in the middle of the image below and the things in the quotes below, so:

  • optimal metabolic health
  • great physical activity
  • no antibiotics and optimized microbiome
  • no overweight/optimal low (visceral) fat
  • optimally low inflammation

while also sitting more and moving less. Alongside this came an increase in obesity

At the same time, the use of antibiotics soared. Antibiotics can have a profound impact on the gut microbiome, and there is good evidence that disturbances to the microbiome are a risk factor for CRC at any age. So are inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease, which have also risen dramatically in young people, probably as a result of similar environmental changes.

and high consumption of sugary drinks](https://archive.ph/o/ixtc8/https://doi.org/10.1093/oncolo/oyae239)

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