#327

Very clever. Side sleeping definitely helps me a lot.

#328

Interesting short video on sleep, supplements, sirtuins and NAD.

Take NAD in the morning when your body needs it

NAD is linked to your circadian cycle, so daily dosing is beneficial. Large IV treatments are kind of useless.

3 Likes
#329

Getting enough movement throughout the day and not eating a big meal for at least 2 hours before bed.

Also if you have adhd or excess noradrenaline symptoms generally, microdose clonidine can be amazing. Especially if you suffer from sleep-onset problems.

If you do use melatonin, no more than 0.5mg, most supplements contain far more so you will need to split the tablet. A higher dose can be used only when you need to adjust your sleep hours quickly.

2 Likes
#330

Wearing clonidine patch 0.1 mg/week allows a very slow release of micro dose. I believe it helps me to relax at night.

#331

Different people have different views on this.

1 Like
#332

I’m having my best sleep of the decade using higher doses of nighttime melatonin. It has also changed my lifetime small bladder/incessant need to urinate, both in the day and at night. I’m also less stressed generally. I’ve heard anecdotal reports of people having my experience and those for whom melatonin induces urge to urinate, so :woman_shrugging:

I am banking on the many other positive properties to melatonin, so hopefully this will give multiple benefits.

3 Likes
#333

@Nlo I’m just seeing it may help our small bladders! I have noticed I have to ‘go’ less often these days and perhaps it’s related?

I never take it before bed any longer and only when/if I wake during the night….because want to be like @John_Hemming :slight_smile:

It works EVERY. SINGLE. TIME.

Also, I’ve probably shared this, but in the event I haven’t…. I started taking LDN a few months ago and after a horrible two weeks of adjustment, my sleep is now next level. I heard them discuss LDN on Attia recently, so I’ll look for the appropriate thread and post it.

2 Likes
#334

That’s nice of you. I want be like @John_Hemming as well.

3 Likes
#335

How much are you taking? At what time?

#336

It varies. I take between 40 and 60 most nights, but more or less depending.

I try to take a 5 mg dose an hour or two before bed when I am home and able to get in bed at my usual normal time. Then I take a 10 mg delayed release, and +/- a 20 mg capsule before turning out lights and then another 10 mg delayed release, or a 20 mg capsule or a dissolvable 5 mg on any wake ups.

I am traveling right now, so not going to bed on time, nor taking my prebed dose. Last night I was out with family late, drinking lots of wine and eating heavy meals. Still, with melatonin, I slept heavily in bouts with very vivid dreams. I did wake up once or twice and took more. However, despite a 4 AM awakening, I took another 10 mgs of melatonin, did not stress, and fell back asleep until 7 AM. No particular grogginess. I mention this because before starting melatonin, a night of wine/food would have me up to pee dozens of times, worried that my sleep was ruined, and stressed that 4 AM would be too late to take anything and that stress would not allow me to surrender back to sleep. Not sure why I am responding so well to this substance but I’m grateful.

1 Like
#337

All you need to do to this is to add pantethine and DHM to reduce the acetaldehyde harm. The problem with this for me is I end up drinking more.

#338

@John_Hemming, are you saying that on the nights I do have a little red wine, I might sleep better and avoid the hangover if I have pantethine and DHM supplements ?

If so, how much, and at what time do I take them, and are there any potential downsides that I should be aware of?

EDIT:
HUH???!! I just found this…
‘In Japan and China, pantethine is available as a prescription drug for hyperlipidemia’

#339

“…pantethine is available as a prescription drug for hyperlipidemia”

I think combo of pantethine and citrus bergamot increases effectiveness.

1 Like
#340

Pantethine can extend bleeding. It is a non rate limited precursor of coenzyme A, a sort of vitamer of B5.

Panethine and DHM may prevent the hangover, but you need enough water as well.

Ideally take them when you are drinking, but a little bit later is OK. Once you have the hangover is too late.

I am not aware of any country where Pantethine is restricted. In the UK I buy it off Amazon.

2 Likes
#341

@John_Hemming In the way it might help prevent the hangover, do you think it would help prevent my heart rate from soaring while I sleep?

I found Double Wood DHM 1000mg and Source Naturals panethine 300mg. Do those sound like reasonable doses to try?

I don’t drink often, but I’ll give it a whirl in the event it makes the experience less regretful.

@Phillipe… interesting!

#342

It won’t prevent an increase in HR or reduction in HRV

#343

I’m excited to try this.

#344

A few years ago I bought Double wood. It reduced, but did not eliminate, hang over. A serious brand.