I think it’s ‘free testosterone’ that is the most relevant marker
I’m not well versed on the literature of TRT, what are the risks associated with higher dosing?
Think we should keep the discussion geared towards the science as opposed to just accusing agetron as being irresponsible.
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Agetron
#423
And, hence you get into the debate of someone who is adversly against TRT (yes I am under a doctor’s care) or an argument againt protein (vegan diet and beans rule), but more protein in an elderly age is important. Not into winning… or a political debate. Let people try what works for their phenotype.
All you manage to do is shut down infomation. There are a number of physicians that will never accept or agree that rapamycin is anything but harmful. That is why it is so hard to get an off-use prescriptions and people are hunting their rapamycin all over the world and questionable sources. Too bad.
Was asked my opinion as a primary source and gave it – I find it odd when questioned on personal experience and opinon by a person without personal experience. Like a lot stuff on here some is helpful… some I find of no interest - some possible harmful.
FYI - my “Testosterone” is not so high I feel the urge to fight, attack or win! Don’t have roid rage… lol.
Within normal range… yes upper normal, but normal. Have a look from a few weeks ago. 
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Your total T is over double the top end of the range @midage_runner posted above… Exactly what I predicted 
Though I still think you need to test free T…
@Maveric78 you are misreading the units in the results. Look again at the normal range included in the report.
@Agetron I wonder what are your SHBG, DHT and estradiol levels given you are at the top of the range. What about red cells? No need to post full pictures, you can write your results if you have them.
Agetron
#426
Look to the right for range. Normal varies on test 199 to 1586. In Comments… under 199 you get a Low warning over 1586… you get a High warning.
I am at 1478 in normal range. Not sure where the argument is?
All my numbers tend to be in high normal… which is where my GP likes to have me healthwise.
No warning comments.
Levine age test has my biological age at 53 based on my last results… 11 year younger difference. If you believe that test.
TruMe DNA methylation came back yesterday from spit… biological age 54 years. Consistent for 3 tests every 6 months last year and a half.
For what it is worth.
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Over double the average 25 year old
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Agetron
#428
I see where you are coming from.
Each laboratory tests differently.
The normal range is on the lab test.
My test normal is 199 - 1586
These don’t correspond… different sources and measurements. Thats all. Like comparing apples to oranges as they say. That is a challenge with any numbers and the range.
I trust the lab knows what it is testing and what results mean. So I go with the lab work.
If something is wrong they identify it. I do labs every 3-4 months for past 5 years
Also not going for average mid-range… I go for average optimal… vitamin B-12; vitamin D, rapamycin; testosterone… etc. All highest ranges within normal.
It looks an odd chart in that it dips quite a bit for 30-34. I wonder if that should be 621 rather than 521.
The range in the UK is 8.4-26.7 with a mw of 288 that is 2419-7690 divide by 10 to get deciLitre values.
Hence top of the range from my current UK lab in dL is 769.
On Maveric’s table 1478 is above the 95% range. I wonder if the measurement is something else entirely. My UK results are compatible with Maveric’s table.
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Age-specific middle tertile levels were 409-558 ng/dL (20-24 years old), 413-575 ng/dL (25-29 years old), 359-498 ng/dL (30-34 years old), 352-478 ng/dL (35-39 years old), and 350-473 ng/dL (40-44 years old).
So almost three times an average 25 year old by this recent research… That’s quite concerning
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Agetron
#431
Maybe it is 3x’s the average 25 year old by this chart. Reiterating that on my recent lab test - my numbers “T” are normal. Not normal for my age - just normal acceptable labs - no worries.
My physician who assists “me” through monitoring my results and his best medical opinion - in “my choices” taking control of my health plan which includes taking rapamycin (against other mis-informed doctors) feels confident in my benefits and health with rapa and TRT over the past 3 + years – therefore is of the opionion to stay the course - unless something changes. My benefits in physical health and looks are undeniable in his view.
So why even bother to share my healthcare choices. Those males in their late 50’s or early 60’s - or even 70’s I guess - might want to consider the combo. Like deciding the right rapamycin dose - free choice - living healthier and younger is great.
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zazim
#432
I wish they had an average for 60-64. Mine seemed a little low the only time I had it tested, which was this year. 459. For what it’s worth, Quest defined the normal range as:
250 - 1100
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Agetron
#433
Damn - I was at 400 about 8 years ago and my GP’s attitude was its good enough. Second GP was as bad - okay for your age. Glad I persisted. Last 3 + years have been golden.
But like with rapamycin - they say no - then it is no. And, I get it, granted they are watching out for their credientals in this litigious world. So to error on super cautious is their goal. Most GP’s see you once a year for a physical - or annual check-up so not at your full potential - it is no big deal.
I suggest you look for and get a GP that listens to you and assists you in your choices not theirs. Found mine on the third try - See him 4-times a year minimum - Never felt better.
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My testosterone test below a few months ago. My free testosterone was also at the high end of the range. I don’t take TRT. I asked my doctor if my test results for my age (67) were surprising - she simply said no. I was training for a short triathlon and getting a lot of sunshine - I bet the results would be less if taken now in the winter.
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Yes I would agree, 400 for a 50 year old looks healthy and normal based on the above data. Where you are now is not. Had you just lost weight and begun lifting weights 8 years ago you would raised T naturally.
But to reiterate, FREE testosterone is the key marker.
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zazim
#436
Insidetracker thinks the optimal levels of testosterone are 460.4–1100. So I was close there. The one that worried me was the more important one. My free testosterone was 6 ng. That and WBC were among my worst markers. They would say 8–22 is optimal. I need to get retested and see what if anything has changed in the last six months. My sleep has certainly improved.
I think I will start lifting weights again. At my age it’s almost criminal that I’m not. Chalk that up to Covid.
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Agetron
#437
Oh definitely need that regular muscle resistance and cardio. Every anti-aging expert seems to agree.
All the TRT in the world is no good without solid, regular workouts to get any muscle benefits.
If you don’t have the energy or stamina that workout is even tougher.
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zazim
#438
Of all the drugs and supplements I have taken lately, there is not a single one that I can point and say that it has helped. I never notice any improvement, including from rapamycin. A possible exception is the long-term fasting because it did improve my blood work and metabolism.
But at age 61 my Levine score was 56, and my biggest complaint when I would go to the doctor was that I always felt tired. He said it’s because I’m getting old. At age 63 my Levine is 50 and I never feel tired. So perhaps there is a cumulative effect!
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I started taking rapa 4 weeks ago (4 milligrams once weekly with olive oil) and experienced severe leg cramps while jogging for the first two weeks. I wasn’t sure if the cramps were rapa related as I couldn’t find any reports of leg cramps associated with rapamycin use but looks like I am not the only one to experience this side effect.
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Bicep
#440
Yup, happened when I first started too. I was working my way up and bam! I had a couple other mild side effects but this was by far the worst.
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