Palliative Care Per Rectum | Palliative Care Network of Wisconsin.

David, welcome to the forums. Is this delivery method (rectum) something you have personal experience with, regarding rapamycin? Did you do any testing to see how well it worked?

I am aware from posts in this forum that siraboon does have good purity and presence of Rapamycin . However it seems from blood tests that oral doses do not give the desired results due to a sub standard enteric coating I can only assume . So given this , I think that PR may work . I donā€™t have access to rap blood tests , so is anyone able to do the honours with PR SIRABOON ? I have no special expertise or experience by the way apart from what was in the link I posted previously .

I already documented all my blood test with Siroboon 2mg tablets in another thread. Look for Siroboon Lab Blood Test Results

Yes many thanks for that thread Adrian , I was wondering if anyone could just administer siriboon PR and do some tests , as it might be way ahead with a crappy coating so to speak !

PR admin WIKIPEDIA article : any medicine can be given this way and bioavailability is always higher and quicker ::

lol, i do not want to that way lol. I use a separate enteric capsule to protect the pills. Cost like $15 for 200. I can easily put up to 3 pills into one.

1 Like

Fair enough . But from what Iā€™ve read , bioavailability is possibly many fold more than even the enteric capsule route . So was just wondering if someone had done the blood work PR , so if people do want to use that route , they can optimise dose

People have brought this up before:

But Iā€™m not sure anyone has tried it yet. Seems like an opportunity for someone! Perhaps doing it only once a week or once every two weeks (or even 3+ weeks) it might be not so intolerable.

If anyone tries it, please do the blood test 24 hours afterwards and report your results!

2 Likes

What brand are you using? Have you done blood testing an hour or two after consumption, to verify the rapamycin made it past the stomach and into the small intestines? Iā€™m considering these; quite a bit more expensive, but still cheap compared to the hard pills. ~$50 for 100 size 4 empty capsules, and theyā€™ve been tested.

1 Like

Okayā€¦ I heard of this the other day in Palm Springs, CAā€¦ donā€™t ask howā€¦hahahah! And, yes - my response was WHAT???

Booty Bumping - slang for taking drugs in your rectum (typically cocaine).

But heckā€¦ why not rapamycin and do a Labcorp test to see how much was absorbed into the blood stream.

Here is a how to guide. Good luck!
Link: Booty Bump: What It Is Boofing? How Itā€™s Done & Risks | Zinnia Health

So glad I get my rapamycin in coated pills by prescription from my Personal Physician. LOL

2 Likes

This thread may yet get merged to the ā€œhumorā€ thread :wink:

Someone her will try it, Iā€™m sureā€¦ just be sure to report back on your results.

2 Likes

I have published my blood results somewhere in the forum ā€¦ have done over 30+ blood test just for siromilus alone. I do not plan to use the enteric capsule anymore as the results shows that the timing of taking the pill affects the siromilus level in your blood more. I prefer to do the blood test at day 3 or 4 days to see that it is above the 3ng/mL threshold. One of my blood test after 12 hours was over 40ng/mL.

Last week I had 10mg with GFJ. My 85 hour test is 4.7ng/mL. So I can safely say that on day 4, it should still be higher than 3ng/mL, may be even into day 5. Anyway, that is enough and hopefully my health will keep getting better.

2 Likes

I have just taken the Rapacan Biocon pills, and when I broke them out of the blister I was surprised to see them scored in the middle, implying you could cut them in half. These are 1mg pills. Why would you encourage people to cut the pill in half - wouldnā€™t that obviate the enteric coating? On second thought, the pills donā€™t have a particularly shiny surface, so I wonder about the enteric coating in the first place. This is from Jagdish, and an established brand. Ultimately I want to test my blood levels of rapamycin, because there is really no other way to know.

1 Like

I think it is the moulding they use, I wonā€™t split it in two. Take longer breaks instead and see if your body gets use to it.