I have tried to use 6mg a week for antiaging, my menstrual cycle is normally very punctual every 33 days, my sex hormones and fertility hormones are very good, even AMH over 4 ng/mL, … which is very high for my 37 yrs.
So suddenly even first month after taking rapa i got delayed menstruation, stopped it and tried again it again happened.
I kinda freaked out and stopped the experiment.
I was reading some trials and if i remember well this could be a sign of it working, so drastically slowing my ovaries? but sitll i am afraid to use it like this
last time i got menstruation earlier, but this is after already stopping rapa for 2 months.
Bryan Johnson’s decision also got me thinking.
I guess i Have to do some reading
on a side note: has anyone tried omipalisib?
Have you reviewed the relevant threads from this story? Rapamycin for Fertility and Menopause; Clinical Results
@medaura took 5mg for almost a year prior to pregnancy, did you see any changes similar to what @Forever29 has seen?
Also - other threads:
yes i read a lot on it and concluded it’s safe to take 6mg, i dont know if it matters but my hormonal levels are more in line with late 20s, and I look unusually young. but still freaking out over aging so want to slow it down
What is your weight? You may want to start at a lower dose (e.g. 3mg) and see how it goes for a while, then slowly increase.
i trialed lower dose too , dont think that was an issue actually unless i need 1 mg, and why would 6mg and later 5mg stop my cycle? wish to understand the mechanism before taking it again
Can I read anywhere more on what Bryan Johnson shared that rapamycin could cause an increase/acceleration of aging in humans across 16 epigenetic clocks?!
I will make my usual point of considering a lower frequency.
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See these threads for why Johnson is wrong on this:
I recommend you listen to this podcast where they talk about epigenetic clocks and current use. In short, epigenetic -related aging is thought to be one small but undetermined part of aging, and the clocks today really are not valid for any decision making by consumers.
Hi !
I am 37 too and the same thing happened to me. According to Chat GPT this is quite normal, it means it worked well 
Could we chat together in private messages ? 