#21

Steve - this issue has been covered before in these discussions - I recommend you check them out:

here: Rapamycin enteric coating vs powder bioavailability

here: How many are making their own solutions from powder?

here: New Peter Attia interview w/Matt Kaeberlein, inferior bioavailability of encapsulated rapa

related Sirolimus Powder - 3rd party analysis

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#22

Thanks, that is what I thought. Enteric coating is the only “improvement” to enable better absorption in the lower digestive tract as opposed to the stomach. And there appears to be a bit of a stability issue to look into.

Fortunately I have enteric caps in stock and the ability to fill them accurately.

To date I’ve just been using the powder for skin care.

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#24

Just take it 3 hours after a meal. The stomach acid should be the lowest by then. I get the best blood result like that.

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#25

I was approved for the compounded rapamycin just this week by the ageless group.
I started on the sirolimus 1mg about 3 weeks ago, then upped to 2mg last week.

Has anyone been using the compounded rapamycin from the ageless team?

I’ve been taking the sirolimus just once a week. I’m also on Diltiazem which somewhat acts like grapefruit juice I’ve learned.

Thanks!

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Cardiac disease and use of rapamycin