#22

I lost about 15 pounds… no fat left to lose… lol. All shredded muscle now.

I stay at about 183 pounds.

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#23

I just love :heart: that explanation !

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#24

So far it appears I’ve lost nearly all of my visceral fat as well. I say appears because I’m currently basing this on my home bio impedance scale readings which puts me at a 1. I’ve been tracking body composition estimates with the same scale for the last 14 months. I’ve asked my husband for a dexa scan as a gift for Christmas to confirm. I also have visible abs which I’ve never had before fwiw. I’m a 54 y/o female and for me it was closer to 6 months on rapa for this change to start to occur. I’ve lost 13 pounds but my weight didn’t budge whatsoever in the first 6 months. Since I generally feel better I added in resistance training which certainly helped and seems synergistic with rapa. I’m not sure if it’s just me or if it takes a little longer for this impact to happen (when it happens) in women.

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#25

Great work. Can you tell us about your regimen regarding, exercise, diet and other interventions.

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#26

Yes, I’m on 3mg rapa weekly since 1/6/23 (5’1/97 pounds). Other supplements include:
Taurine 2g QD (previously 1g off and on for years)
Melatonin time release 20mg QD before bed
Multi vitamin/mineral (most days)
Glycine 2g QD
*5-Htp 200mg before bed
*Lithium orotate 5mg (most days)
Estradiol patch .075mg (not for longevity specifically but for menopause)
*Creatine 5g
Dhea 25mg QD
Vitamin D 2k/5 days per week
Exercise:
*Weight lifting 3x weekly
Walking in weighted vest 30-45 minutes 3-4x weekly
Starred items are things I’ve added since starting rapa which definitely could have helped. I’ve also improved my less than optimal diet by reducing fat and adding more fibrous vegetables.
As an average woman who is learning as I go so I’m definitely open to fine tuning my longevity approach. I think we should always be open to learning and adjusting as needed.

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#28

woman here and I’ve been on rapa for about 5 - 6 months. No weight loss. I’m a runner and at the gym (Crossfit and Hiit) 2x per week, pilates and gyrotonics 1x each per week. And I run about 25k per week. I have now cut wine and calories (mostly fish, some chicken breast, low carbs) for the last month. I#ve seen a little budge…maybe a kilo. Still waiting for the magic.

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#29

I can relate. For the first time in my life…over 65, I’m having a tough time w weight and also a spreading middle. I find it v weird. rapa has had not impact as far as I can tell. Perhaps it helps with recovery after exercise. I can do more and still have good HRV and recovery (Oura ring). But thats it.

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#30

I finally have the luxury eating everyday whatever I want… as much as I want… all day if I want. My weight hovers between 181 and 183 pounds. It has for the last 4 years, on rapamycin, it’s like my weight point reset.

I like where i’m at.

Everything is solid muscle with no extra fat. I just did a second DEXA scan my BMI is twenty five and no visceral fat. Same as 2 years ago. Will do bone test in December ( when insurance kicks in for a retest). Hoping Taurine has improved bone… or at least no change. I know that the reason i’m able to not gain weight or that I can eat so much wuth no change…
has to be because of the rapamycin.

My son lost twenty five pounds after three months of rapamycin, but he was thirty two years. The weight has stayed off and it’s been a couple of years. He does rapamycin 2 mg every two weeks.

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#31

The luxury of eating every day, how impressive.

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#32

Someone here needs try this out:

Polar reveals new visceral fat measuring technology for wearable devices

Polar is working on a new visceral fat measurement tool. Visceral fat is stored around internal organs like the stomach and liver and has been linked to health conditions such as diabetes and heart disease. However, it has historically been harder to measure, with previous methods including a CT scan or MRI.

Rumors about this new Polar technology started when a patent filing for a dual-purpose wearable strap was uncovered earlier this month. The document describes a device that could be worn around the chest or abdomen, with the ability to measure heart rate and compute “a quantity of fat tissue in the abdominal area on the basis of the received body composition measurement data”.

In a recent interview with Wareable, the company has officially confirmed that it is developing this technology. Polar representative Jari Miettinen said the company wanted to “bring a more sophisticated level of health monitoring to wearable devices”. However, they would not confirm whether or when the visceral fat measuring feature could reach a consumer wearable, stating that “this remains an active area of research, with decisions on potential commercialization to be made based on further results and strategic evaluations.”

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#33

I wonder if this might be the mechanism of visceral fat reduction with rapamycin:

Autophagy is a highly conserved cellular recycling process essential for homeostasis in all eukaryotic cells. Lipid accumulation and its regulation by autophagy are key areas of research for understanding metabolic disorders in human and model mammals.

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#34

Reasonable argument… I lost at least 20 pounds of visceral fat after 3 months of rapa dosing… it just melted away – a pound every few days.

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#35

Well, I did not lose 20 pounds of visceral fat in 3 months (your steak eating self has definitely won the genetic lottery!!!), but I just did my DEXA, and from my last DEXA 3 years ago, I went from 1.37 lbs to .84 lbs visceral fat.

I lost 4 pounds in that timeframe, so I guess some of that is natural. But, I gained 1.5 pounds of muscle (I barely have any in the first place, so the bar was low).

I’m doing more resistance training and started rapa. I’m only sharing incase some of it was from the rapa, but I have no way to know!

My numbers are meager and I don’t expect a parade, but my aging self will take what I can get!!!

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#36

Whoo…hoo!
Congrats. Any numbers in the right direction as we age is fantastic news.

I started losing a pound at 3 months… rapa use,. but definitely had lost 20 pounds within a few months (it was mostly visceral according to my physician)… as my body size and look stayed the same…I lost the hidden fat. Once it started falling away… kept losing until it was gone.

I think guys can knock fat off a lot faster in general. We can get to a smaller BMI… not even achievable by women… based on charts… and body images.

Your muscle :muscle: growth is pretty fantastic… the older the harder it is to gain.

Looks like rapamycin is a great choice… eliminating what is not needed…growing what is needed…continue measuring and keep us posted.

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#37

What an enthusiastic and motivating response! Thank you!!!

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#38

Physionic just released this video on visceral fat reduction.

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