#1

Thoughts on this issue? I am bouncing around mowing on my John Deere Rider for 3 hours today - and it suddenly hits me that I am having zero allergy response - it’s been raining the past 3 days and is now hot and humid - everything is in bloom. Typically I will have red itchy eyes and runny nose. It occurs that I have had no allergy response for the past 2 summers (I typically rely on several bottles of Flonase early summer and early fall). All my life I had been allergy free until I hit my early 50’s and then it has gotten progressively worse.

Thinking about it… rapamycin is an immune and inflammatory modulator…during a reaction, your immune system releases antibodies. These are proteins that deliver a message to cells: Stop that substance! The cells then send out histamine, which causes blood vessels to expand, and other chemicals, and these trigger the allergy symptoms.

Hate to say rapamycin fixes it all - lol. But, my allergy issues currently are non-existent - living in Missouri the armpit of allergic substances makes me wonder.
My immune response is like when I was much younger - no problems.

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Rapamycin User Update after 7 months - Periodontal & Allergy benefits
#2

My allergies have gotten a lot better the past few years while I’ve been on rapamycin, but not sure if its just within the normal variance I have experienced in the past. But generally - my allergies have gotten much, much better. Interesting… I had not thought to consider rapamycin as the reason behind the improvement.

I used to get major seasonal allergies every spring - from pollen and dust.

Anyone else?

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#3

I’ve been on Rap for about 4 years. I’ve noticed no improvement to any of my seasonal allergies, dust and food sensitivities.
.

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#4

So maybe RapAdmin and I are… N=2
Thanks.

#5

I had the usual seasonal allergies real bad starting in my 60’s.
Lived on sudafed and tried all the allergy meds and they helped.
When the covid mess came up I started taking large doses of Vit-C,
D-3, Zinc, and K-2. I noticed the next allergy season my allergies
were almost non existent and have continued for two years or more.

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#8

I absolutely noticed a difference my first summer of taking rapamycin. I am a 53 female and live in Alberta, Canada and I’ve had seasonal allergies since the birth of my last child in 1999 along with a sudden anaphylactic reaction to stings (never had allergies of any kind before the birth of my son). I have been taking rapamycin for almost a year (4mg, 8 weeks on/off) and normally start taking two different antihistamines daily starting around June 1st. (Claritin and add Reactin when the first one just doesn’t cut it). I have not been able to mow the lawn due to the severity of my allergies and eat them like candy until at least September or October and have to take them intermittently year-round due to allergies to dust as well! I can’t remember when I stopped taking my antihistamines but noticed pretty quickly in June that my allergies hadn’t kicked in yet. It is now October and I have only taken one antihistamine twice during the entire summer!! As one who watches pollen reports on the daily I can tell you that everything pollinated as usual, the only difference was I was on rapamycin. I can’t prove it as yet but am totally convinced. Now I’m watching my toe nails with baited breath hoping they might grow back normally from a toenail fungus at a swimming pool when I was young. I heard some people see improvements with that and gingivitis or periodontal conditions. Fingers crossed!

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#9

Too good to be true… but several on here who started getting allergies as they aged, no longer have allergies after a year of rapamycin.

I wrote this topic 3 years ago… and allergies are gone… ragweed season here… everyone seems to be suffering… but not me. Fantastic!

As to the toe fungus… rapamycin does a lot, but it didn’t help there. I tried almost every topical medication.

But, nothing kicked it until I took Terbinafine for 3 months. You want rid of it… see your family doctor and get a prescription. Why be embarrassed with yellow toenails. And it can’t be healthy.

Here’s my pics of fungus to clear in months.
Lived with it for years.

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