I have a question. My BP is quite stable and last two days I have seen a sudden drop of around 5+ points. I introduced 3g l-citrulline (actually malate) as part of my morning shake and I reduced my salt intake (roughly from 4g sodium to 2g sodium) starting Monday. Part of my shake is also banana (roughly 400mg potassium?), but would this cause the decrease of 5+ points?
Should I ditch the citruline? I don’t worry that much about systolic but diastolic went from 66 (average of last month) to 60, which might be too low? And my nighttime BP 92/55 is also quite low…

Anyway it has only been two days, maybe it is just noise but my BP is quite stable otherwise…

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I am very sensitive to potassium’s effect on my BP. But your BP shown is about where mine is when it check in the AM. I don’t have any issues at that BP.

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The number is average of last week, usually it is around 112/66… (and i am perfectly ok with it)
Last two days seems to be 103/61 on Tuesday and today 101/60… (that is daily average).
Diastolic below 70 is associated with increased mortality and reduced tissue perfusion…

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I’d only worry about it if I had reasons to think I was unhealthy. To raise it I’d skip the potassium.

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Thanks for this, I wondered what was happening to mine as well. I went from a very consistent 120/80 to more like 110/65 and now that I think of it this happened after I bought a big bag of citrulline and started dumping it in with my glycine. I’m not sure this is bad, but it’s nice to know what happened.

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Here is something interesting posted on X:

Pulse Pressure implications

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One of the intended functions of Citrulline is to reduce BP. If you feel your BP is getting too low, then I would cut back on the Citrulline. For me, I could really use a 5-10 pt reduction in both BP figures, so that’s why I take Citrulline as well as for the Nitrous Oxide.

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The trend continues. I did not know Citrulline was that powerful. I thought I would not notice anything from the small dose. Today I omitted banana in my smoothie. Still dropping. Now we have sodium and Citrulline to test. Both interventions are new from Monday. I don’t feel like my BP is too low, i feel completely normal. I tested my BP on manual device too.

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Nick Engerer:

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Do they sell Aktiaa in the US?

No, not yet. You’d have to use one of the re-shipment services in the UK or EU, and it would likely only work with your phone if its Android (apps are only available in Europe, and the apple phone is more “rigorous” in preventing you from loading apps from outside the US.

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Here is a description of the basis and use of “pulse pressure” which is the difference between systolic and diastolic BP

Physiology, Pulse Pressure - StatPearls - NCBI Bookshelf.

“Aging impacts pulse pressure and arterial compliance. With aging, there is a decrease in the compliance of the large elastic arteries. This change is due to structural molecular changes in the arterial wall, including decreased elastin content, increased collagen I deposition, and calcification, which increases the stiffness of the wall. This process is often described as “hardening of the arteries.” As the left ventricle contracts against stiffer, less compliant arteries, systolic and diastolic pressures increase and can result in a widened pulse pressure. In response, the left ventricular tend to hypertrophy. When excessive pulse pressure transmits through the microcirculation of vital organs such as the brain and kidneys, extensive tissue damage tends to occur.[8]

“A pulse pressure that is less than 25% of the systolic pressure is inappropriately low or narrowed, whereas a pulse pressure of greater than 100 is high or widened.”

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Additionally, however, an increased Stroke Volume will increase the pulse pressure. Hence there are the two factors, the elasticity of the arteries and the stroke volume.

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This study reveals some nuance regarding age.

“In younger individuals, regular exercise was associated with lower diastolic blood pressure but elevated pulse pressure. In contrast, both systolic and pulse pressure were lower in older active individuals, compared with their sedentary counterparts. Moreover, regular exercise was associated with lower wave reflections and peripheral vascular resistance in younger individuals, but lower large artery stiffness in older individuals.“

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I think this relates to the issue of mitochondria efficiency in the heart. If you can improve mitochondria efficiency your stroke volume will go up. I think this is what I did more recently by taking a large number of AMPK activators (as well as intermittent rapamycin). Initially my PP,SP and DP went up, but then SP and DP came down gradually whilst PP has remained higher.

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Here are some reviews of different options.

(Think the Omron Watch is back in stock now)

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I tried the BP feature in the previous Galaxy Watch: not reliable at all.

Do we have independent scientific papers for these devices?

(receiving my Aktiia today btw… Ordered in Dec)

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At least the Omron probably should have as it is FDA cleared, which even Aktia is not (yet) and FDA tends to be stricter that EU or UK on devices.

Let us know how it goes, and please compare to standard arm-cuff BP monitor results.

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Yes the Samsung one is approved in the EU even though it just gives random values…

I found this: Comparison of the Omron HeartGuide to the Welch Allyn ProBP 3400 blood pressure monitor 2023

“Based on the significant differences between the HeartGuide and Welch Allyn, our data indicate the HeartGuide is not a suitable replacement for existing BP monitors.”

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