#61

“Nature is just as happy to kill us as she is to nurture us.”

Totally agree. It’s foolish to think otherwise. I live on the ocean and spend a lot of time in it. I know that it will kill me in moments - there is no caring no coddling. Yet disconnecting from the currents, the waves, the tides only makes things more dangerous. The better tuned one is to the forces, the better off one is. Simple rejection or attempted isolation from the natural world is not a sustainable strategy.

Respect and wise informed orientation are best yet should not be mistaken for blind trust or submission.

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#62

The mother nature is no longer the mother nature we cuddled in decades ago.

  1. Ozone layer destroyed and not fully recovered yet, you are directly facing the ultraviolet radiation damage.

  2. Greenhouse effect make the temperature much higher than before, weather becomes much deadlier, heat stroke may kill you if you’re outdoor too long.

  3. Ocean filled with medical waste, unknown chemicals, plastic particles, and Fukushima radioactive discharge…

  4. The air you breath in contain high PM 2.5 pollutants, rich of heavy metal released from nearby factory, car exhaust, etc, harden your blood vessels and cardiovascular system and kill your immunal system in minutes.

  5. Herbicide and pesticide on neighborhood lawn, Walk by you and your pet will bring them home, probably cause you autoimmune problem.

  6. No need to mention potential car accident, and gun shooting frenzy, effectively end your life earlier if you stay outdoors…

Anything i missed ?? Let’s do some math to see which outweigh which.

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#63

Yep, I also noticed that most of those referenced had little relevance.

#64

And maybe use astaxanthin during summer.

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#65

I can’t believe the body is choosing to convert that glorious previtamin D3 with all of its magical health effects after UVB exposure… to Vitamin D3!

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#66

Hi @Godel_Chen , Can you tell me about the solution you apply? Have you seen any results yet?

#67

May i know solution to what?

#68

Ahh sorry, I mean your DMSO rapa + metformin solution , that you apply to your hyperpigmentation?

#69

It seems the darkest spot on my left upper cheek a little bit lighter than before, but i am not sure if it’s just placebo effect or not.

Protect your face from sun exposure at the very first beginning is the better strategy, i didn’t give it a high hope that those spots will go away any time soon…

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#70

Thanks for your reply, I’d love an update if you notice improvement. I’m trying to help my mum who grew up without sun protection habits, so the damage is already done sadly. Best so far has been hydroquinone, but the damage becomes visible again too soon/easily. Good luck with yours!

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#71

I have just begin my topical rapamycin and metformin use 3 months ago, therefore it’s natural not yet to see much differences. However, some clinical trials already show some very promising results.

Let me show you one clinical test result, which also being shown on other talk in this forum.

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925069/

Topical application of 0.6% metformin cream alleviates the manifestation of skin damage in UVB-challenged mice.

Metformin inhibits the secretion of IL-1β and cell death in UVB-challenged keratinocytes.

Metformin treatment inhibits the increase in expression and nuclear translocation of C/EBPβ in UVB-challenged keratinocytes.

https://www.sciencedirect.com/science/article/abs/pii/S0923181121000141#:~:text=Topical%20application%20of%200.6%25%20metformin,death%20in%20UVB%2Dchallenged%20keratinocytes.

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#72

I’m in Auckland New Zealand right now and the one thing I’ve noticed about the 60+ crowd is their skin on their hands and face are horrible. It looks like they’ve received radiation burns (which they have as UV from the sun). Those in the 80+ category are much much worse.

The sun causes a lot of damage that just doesn’t show up until you’re over 60!

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#73

They can outlive you even with skin cancer, according to the lady professor mentioned above, skin as the receiptor can take all the benefits from sun exposure to protect internal organs from diseases, like heart attack, mental problem, etc.

It’s like sacrifices skin for the greater body good.

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#74

If the skin ages and increase the risk for skin cancer from it, you are not going to live longer from sun exposure.

You will live shorter, and also more miserably as you damage not only your skin but everything else that is irradiated, depending how far it penetrates. Blood vessels and things transported in the blood can be damaged too. But the skin apparently absorb most of the harmful rays, so it won’t damage other organs.

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#75

There are NO benefits of ultraviolet radiation!

It will destroy your eyes too and suppress your immune system.

https://www.who.int/news-room/questions-and-answers/item/radiation-the-known-health-effects-of-ultraviolet-radiation

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#76

Sunlight or sun exposure is NOT the same thing as UVA/UVB radiation, choosing to not use sunscreen, or not wearing UV protective clothing.

UV protective clothing + sunscreen gives you the benefits of sunlight without the risks and without the skin aging from UVA (note: glass does not block UVA).
Sunscreen use has detected no evidence of increase harm. This means it might be the NIR light (near infrared light) that goes through clothing, sunglasses, and sunscreen.

I didn’t realize this. :man_facepalming:

Literally SUN EXPOSURE includes when wearing UV protective clothing, hats, and all (NIR light goes through it, maybe 50% reduction for denim…) !

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#77

It’s all about the dosage. Don’t get so much that you burn. But you do need UVB to live healthy. Naked at noon is a book title and also a good strategy because UVB is in higher concentration when the sun is directly overhead. Working outside in early morning and late evening is cooler, also you get the NIR without the UV, because UV does not make it through the atmosphere sideways.

I use my lights nightly after my shower, so skip the UVA and a bunch of the rest of the spectrum. I use 3 Sperti’s and the biggest Platinum they make ( I think it’s a 900). But I work all day in the sun without any protection. Sunlight will not kill you. We’re designed to take it. We actually need it.

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#78

could it be the type of vitamin d (synthetic) isn’t helping all cause mortality in those studies and a more bio available supplement vitamin d would help?

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#79

Exposure to the sun’s UV radiation may be good for you

The risks uv poses are real, but new research suggests it may be time to consider the benefits. According to a study published recently in Health and Place, increased uv exposure appears to make people significantly less likely to die from cardiovascular disease as well as cancer. The risk of dying from melanoma skin cancer, the deadliest form of skin cancer, did not meaningfully change with uv exposure. Although smaller-scale studies have previously nodded at health benefits, this is the largest study to show a direct correlation between uv exposure and longer lifespans.

To conduct their analysis, the researchers from the University of Edinburgh used data from over 360,000 people in the uk Biobank, a database. They identified two cohorts more likely to have high uv exposure: those who claimed to use sunbeds or sunlamps; and those living in sunnier locations. To check that their assumptions about the subjects’ uv exposure were correct, the scientists also looked at vitamin D levels in a subset of blood samples. As vitamin D is synthesised in the skin in the presence of certain forms of uv radiation, it is a reliable indicator of solar exposure.

The new research may prompt scientists and health experts to look deeper into the benefits of uv exposure versus its risks and, perhaps in the future, make available more nuanced advice about how different groups of people can best stay safe in the sun. But for now, experts agree, the study is not a licence to stop wearing sun cream.

Read the Full Story: Exposure to the Sun’s UV radiation may be good for you (The Economist)

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#80

To check that their assumptions about the subjects’ uv exposure were correct, the scientists also looked at vitamin D levels in a subset of blood samples. As vitamin D is synthesised in the skin in the presence of certain forms of uv radiation, it is a reliable indicator of solar exposure.

So as in most studies, it’s impossible to distinguish whether those supposed beneficial effects come from UV radiation or from vitamin D.

1 Like