2:32:49
Now let’s go to autism. Is there any evidence, that inflammation can lead to autism? We have decades of evidence for this. We know that over the course of the last century, as there were kind of outbreaks, of bacterial or viral infection, in the population, we saw higher rates of neuro psychiatric, neuro developmental in the offspring of the pregnant women. So we’ve long known that and that evidence is pretty well established.
Huberman: For instance, forgive me, but the one that I’m aware of is that flu in pregnant mothers at the first to second trimester transition is correlated with statistically higher incidence of schizophrenia in the offspring. Do I have that right?
That’s correct, but then there was a rubella outbreak that resulted in much higher rates of autism in the offspring. Um I think that was in 1960s, ah and really decades of animal models. So they take mice, and they inject them with lipopolysaccharide which causes an inflammatory reaction and when they do this to pregnant mice, the mice that are born to those women, to those female mice are at much higher risk for showing signs of symptoms of what looks like a neuro developmental disorder.
My observation: The illness of the pregnant women caused neuro developmental disorder to the offspring; not vaccine to the mother, nor to the offspring.
If you inject a pregnant mouse with lipopolysaccharide, can that mouse still have a normal appearing mouse? Yes. But the probability that the offspring will have a neuro developmental, symptoms of a neuro developmental condition increase.
Same observation as above.
That is where so much of the autism research has been focused. In trying to understand this. Trying to what is happening with inflammation, how does that impact neuro development? We know that.
So now back to the question that you posed. Is there any possibility that vaccines can contribute to that process? **Do vaccines increase inflammation? **
> I think the answer to that is yes.
My observation. Pure speculative opinion; no stats cited, no attribution to any basis for the opinion.
Is there variation in inflammatory response between different people? I think the answer to that is yes.
Same observation as the foregoing.
Can some people have a hyper-exaggerated inflammatory response to a vaccine? I think the answer to that is yes.
Same. But this is true for all interventions. There are variations in responses, whether vaccines, or supplements.