No matter what ai eat or don’t eat, my asthma symptoms increase after about 8pm. Then decrease in the morning.
As albuterol doesn’t help me this means sleep is difficult. I feel great but by the time I want to go to bed I have shortness of breath.
Sometimes I need to drink a strong coffee to get to sleep.
daver
#22
Amira, have you tried getting rid of your asthma entirely with azithromycin, under a doctors care
of course. There’s a protocol, and it completely cured my asthma of 20 years. I had been taking
250 mcg of fluticasone twice a day but was unable to get by on 125 mcg. Recently I ran into a
friend from the past who told me it cured his asthma too, but for him it came back after a year
and he’s now about to repeat the protocol. This is all described in the book, “A Cure for Asthma?”
which is available on Amazon. As high as 50% of people might be cured, usually those with
the asthma most difficult to control, For me, I added N-Acetyl cysteine and some colloidal silver
to the protocol because I think those things make antibiotics work better.
2 Likes
daver
#23
In any event, I would encourage you to take as much vitamin D (along with vitamin k2 and
magnesium) as is safe, as I believe it can help prevent lung damage. There’s even an
unsubstantiated idea that the Coimbra Protocol can stop all asthma as long as you’re on it.
This is not a recommendation though.
1 Like
That’s interesting, thanks. I’ll look into Azithromycin.
I’m taking 5000 IU of D3 with MK7 a day (and magnesium), I was taking double that dose for a few months, but I got scared into lowering it.
I also tried the Russian fasting method, but every time my symptoms became so bad I had to stop by day 11 at the longest.
I have a diet free from seed oils, wheat and sugar. I don’t have any allergies. I was also a long distance runner until I got asthma last year. My lung capacity is still at the average for a 20 year old (I’m in my 50s) when my lungs are clear, which is only with prednisone now.
The doctors want me to start a biologic (monthly injection) to supress the eosinophils next month, as I’m diagnosed with late onset, steroid-dependent, severe eosinophilic asthma, which doesn’t respond to inhalers.
I’m a bit worried what the long term effects of that med might be, but at this point I’m desperate. Also I need to get off prednisone dependency.
As it all started after a mild bout of COVID and I’m basically very healthy, I still feel there is some way to reset this.
They gave me lots of tests to rule out other diseases.
The Coimbra diet looks interesting. I think I’m going to give that a try, I’ll let you know how it goes.
This apparently is me, on the right, nonallergic SEA.
1 Like
Dr.Bart
#25
I would inquire about Tezspire, it blocks TSLP which is higher upstream of the inflammatory pathway.
1 Like
There may be something to the bacterial theory of asthma. When I was a child, I had frequent lung infections with associated asthma. In college and as a young adult, my asthma more or less disappeared, even though I had lung infections fairly frequently. Then I had kids, and one of my sons had a very high fever when he was about 2 years old, and I had to get him to a doctor urgently (ended up being a bacterial infection if I remember correctly). I had a lung infection at the time and didn’t have access to a car, so I biked as fast as I could with my feverish son in tow. My asthma started back-up after that incident and has been with me ever since.
I’ll take a look at that book, thanks for the recommendation.
(Late) update, week 2.
I’m not sure how responsive my asthma is to sirolimus. I take other supplements that may be more impactful, like Berberine and Quercetin. I stopped taking those 12/11, but it’s hard to isolate any one impact. I’m coming to the realization that N1 experiments are kind of useless, but I’ll keep going for a few more weeks and see if anything interesting comes up.
2 Likes
Yeah, but let’s be honest, many of us here are taking powerful medications based on the beneficial impacts seen in mice in antiseptic labs; and based on subjective anecdotal reports from other N1. I would prefer people encourage and report on their N1 results so we can start to get a sense of what works and what doesn’t. Hopefully we will soon have reliable data from well-designed studies support some of what we are experimenting on in this forum.
Update week 3.
Asthma seems to have gotten exacerbated with 4mg rapamycin. This was followed by lower incidence of asthma in the next few days. @PLEIADES reported on a similar effect here.
I decided to continue taking quercetin and berberine, which may have a role in reducing asthma attacks. Obviously these are big confounders, but right now I’m more interested in getting asthma under control without steroids than being a purist about isolating the impact of rapamycin.
Lastly, came down with a cold and will be getting my shingles vaccine in a few days, so no rapaymcin this week.
Update week 4.
As mentioned in the last update, no rapamycin this week due to an infection and getting the shingles vaccine a few days ago. I will wait until this infection clears before starting again.
Good news on controlling asthma, taking GlyNAC in the evening (started 12/25) has removed the need for the nightly puff. There is weak evidence that NAC can be useful in the treatment of asthma; and even less evidence for glycine. Nevertheless, taking GlyNAC at night has completely cleared my nocturnal asthma 
I’ll report 1 more week to confirm the GlyNAC effect is persistent.
1 Like
