#21

Yes - that is about average, or the median. See our poll here: What is the Rapamycin Dose / Dosage for Anti-Aging or Longevity?

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#22

@desertshores What dose of Rapa are you currently taking?

#23

Thank you for referring me back to that thread, completely forgot about it.

#24

5 mg per week is definitely a typical dose. For more detail see the poll RapAdmin linked to.

#25

5mg once weekly with EVOO.

#26

Are you still taking it with GFJ?

#27

Lara what intradermal injections are you doing if I could ask?

#28

I do all kinds of mesotherapy injections for my face and hands. I use Citocare 532, Mesohyal, Korean Ultra White and Ultrahilo. I also used Juvederm products (skin fillers).

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#29

Here’s another

IL-17 mediates immune responses against extracellular pathogens, and it is associated with the development and pathogenesis of various autoimmune diseases. The expression of IL-17 is regulated by various intracellular signaling cascades. Recently, it has been shown that mechanistic target of rapamycin (mTOR) signaling, comprised mainly of mTORC1 signaling, plays a critical role in IL-17 expression. Here, we review the current knowledge regarding mechanisms by which mTORC1 regulates IL-17 expression. mTORC1 positively modulates IL-17 expression through several pathways, i.e. STAT3, -HIF-1α, -S6K1, and -S6K2. Amino acids (AAs) also regulate IL-17 expression by being the energy source for Th17 cells, and by activating mTORC1 signaling. Altogether, the AA-mTORC1-IL-17 axis has broad therapeutic implications for IL-17-associated diseases, such as EAE, allergies, and colitis.

全文（开放获取）：

https://onlinelibrary.wiley.com/doi/10.1002/eji.201545886

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#30