Then there is this study where no statistically significant result was found between topical HA and placebo. They of course try to spin it positively in their abstract and conclusion as it is a company-funded study.
Furthermore, it is difficult to assess the improvement of a topical agent because these are usually subtle effects that might be difficult to capture; other studies have reported issues.28, 31,32 Additionally, the grading scale used to measure efficacy was not sensitive enough to detect differences between the active group and the placebo group. Our study duration was only 60 days, which might not have been long enough to assess the potential of the active topical ingredients to improve skin aging on the neck. Lastly, one of the limitations of the study was the small sample size.
A Prospective Double-blind, Placebo-controlled Clinical Trial Evaluating the Efficacy of a Novel Combination of Hyaluronic Acid Serum and Antioxidant Cream for Rejuvenation of the Aging Neck - PMC (nih.gov)
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Both studies seemed to be funded by skincare companies.
I’ll continue using topically, as I’ve experienced nice results.
Thanks for the info!
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Curious
#245
I use taurine in the form of powder. It idoes not taste that terrible. Some others here here mix it with coffee.
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Taurine and Coffee are synergistic. That’s what I do. I scoop 6 g of nutricost powder into my second coffee of the day which I take several hours after my first coffee which has glycine and collagen.
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nikney
#247
rapamycin, nmn, fisetin, ergothioneine, taurine, acarbose, omega 3, vitamin d, NAC+selenium, astaxanthin
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hi @Beth , i’m late to find your post, but, if you still take Taurine, have you since tried taking a Powder? -
AllMax brand makes one that is Not made from animal sources, and has No Taste,
it’s pleasnt to use, and when I am on it I take either 1tsp (or 3/4 tsp, if i have a measuring spoon available), up to 3 times a day…
…for me, any less capsules i can take, is a relief…
hope this helps you …thank you for your past support… warmest regards…
.
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Beth
#249
I appreciate the idea! After my battle with creatine, I’ve learned I’m pretty sensitive to taste, but there is a chance this might work for me.
I’m taking 6 capsules with my other evening pills and am now used to throwing back handfuls of them. If I should ever start taking them earlier in the day, I”ll give the powder in a drink a try. Thx again
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you’re most welcome! -
and…
i don’t know if you’ve given up on taking Creatine due to the taste of powders,
but wanted to metion -
if it’s worth adding any more capsules
(I’m with you on the handfuls of pills -
it is like a JOB taking so many every day!
…but I hope, worth it…)
…there’s a type of Creatine called
Krealkalyn,
and supposedly, it’s effective enough that you don’t need to take the big doses associated with traditional Creatine.
maybe only 1-2,
and if you’re looking to high dose it, then 3-4 capsules -
but even more importantly,
Krealkalyn claims to Not Harm Kidneys -
which to me, is of the utmost importance! ;
i’d still ask my Dr. for a Kidney panel
after 1 month,
then 3 months,
6 months and 1 year, and every 6 months to see if everything’s okay,
but hopefully it really doesN’T harm kidneys,
and can make creatine supplementation possible without terrible tasting powders, OR many pills!
best of health to you! 
.
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Beth
#251
Have not heard of that option, so thanks. In another thread, the hive mind helped me figure out a way to tolerate creatine powder. For me, the magic sauce is in my tangy soy yogurt
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lol okay
enjoy, and best of health! 
.
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