Any opinion on DMAE? I just noticed the offer a DMAE firming gel at agelessRx

Iā€™m also skeptical about serums and creams and prefer fillers and meso injections that deliver products in deeper layers.

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Latest Dr. Brad update

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Finally, a skincare educator who seems qualified to talk about the science of skincare (not just marketing BS from ā€œinfluencersā€, which from my perspective is 98% of the ā€œskincare informationā€ out there). Are there others like this person that you know of? Please post links to their sites/feedsā€¦ And by ā€œothersā€ I mean well-educated in this area, without ā€œsponsorship dealsā€ that influence their suggestions/reviews and analysis.

Here is the full article (there may be a paywall for some users): https://archive.ph/no1M7

LabMuffin Website / Blog:

Her YouTube channel:

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dr Natlia Spierings, she is on insta. And she will kill many hopes lol.

What Dermatologists Really Think About Those Anti-Aging Products

Cosmetics companies are trying to wow consumers with clinical-sounding ingredients. Actual scientists arenā€™t impressed.

Beauty companies big and small are increasingly using scienceā€”or at least words and phrases that sound like theyā€™re pulled from a peer-reviewed journalā€”to market their products. The dollar value of products sold in the US that say they include clinical ingredients, such as niacinamide and hyaluronic acid (both can help hydrate skin), has been growing at an average annual rate of 71.5% during the past five years versus 5.3% for overall skin-care items, says Jacqueline Flam Stokes, senior vice president for beauty, drug and over-the-counter retail at NielsenIQ, a data firm. The surge in demand for ingredient-led products has surpassed consumer interest in beauty items marketed as ā€œnaturalā€ or ā€œorganic,ā€ which were particularly popular before the pandemic, she says.

Take ceramides, lipid molecules that can help preserve moisture and protect against skin irritation. ā€œCeramides have been a very popular ingredient in cosmetics and skin-care products for decades,ā€ Flam Stokes says. ā€œWhat weā€™ve seen over the last three years, really, is that ceramides are now a popular ingredient thatā€™s being called out on the front of packing labels.ā€

Welcome to the scientification of skin care. The trend gathered momentum during the pandemic, when Americans were spending countless hours eyeing themselves on video chats. That prodded many to try to address their perceived skin imperfections. With guidance from skin-care influencers on TikTok and elsewhere, shoppers snapped up clinical-sounding beauty products to expand their facial routines to half a dozen steps or more.

Full article: https://archive.ph/FPNeS

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An interesting thing happened to me this morning. One of my male colleagues stopped me and asked what I had been doing to my skin. He said my wrinkles were gone and I looked visibly younger than before. I appreciate the comment.

Iā€™m not applying anything extra to my face, but I attribute the loss of wrinkles to the collagen peptides, 10,000 iu vitamin D3 and hyaluronic acid supplements. Somethings working right!

Also, I lost 4 pounds over Christmas. Maybe that too?

Now, I need to figure out what I need to make my hair grow backā€¦ :wink:

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2.5mg of dutasteride, minoxidil (topically or orally if youā€™re feeling brave) and a topical anti-androgen such as alfatradiol, fluridil or Chinese research chemicals such as pyrilutamide or RU58841 along with topical rapamycin will revive any hair that hasnā€™t died yet.
Alternatively you can use 1mg finasteride once daily and topical minoxidil twice daily if your hairloss is not severe yet.

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I already use topical minoxidil. I gave up on finasteride as it put me in a bad mood. Iā€™ll look into the others. Thanks!

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Wow, losing weight almost always increases wrinkles.

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Thereā€™s topical finasteride too which has somewhat less systemic absorption.

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No, It is the opposite. When you lose weight, your wrinkles become more visible, because there is less fat in the face to fill wrinkles with. Also from my own experience, losing weight is always good but not for wrinkles. You can also see that on people with before and after pictures.

edit: Meant to respond to @DeStrider

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He said he lost 4 pounds. Unless every single ounce was lost in the face :laughing: thatā€™s hardly the stuff that will make one look like a deflated balloon.

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the point was that generally speaking losing weight will make wrinkles a bit more visible, meaning if he has less wrinkles it is not because of the weight loss, so he can thank something else for that. lol

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Yes. That too. I do find losing a few pounds makes the face look more youthful though. Just trimmer around the edges. I guess even weight loss has a ā€œU shaped responseā€ on youthfulness.

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My lifetime experience: Yes, losing weight is healthy, but I cannot think of a single person among my family and friends who losing weight made them look younger. Not one.

I should qualify, some looked better, but none looked younger.

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Agreed. The loose skin that wonā€™t go away is maddening. It must be an autophagy thing.

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For a few years, I went on a strict caloric restriction (with optimum nutrition) diet and went from 162 (5ā€™10) to 146. Lost a lot of weight from my face which never returned. Not uncommon I subsequently found from some plastic surgeons. I sure felt healthy but looked like concentration camp refugee. Not good.

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Itā€™s the subcutaneous fat loss which makes the facial skin sag more. Happens naturally w/aging but is accelerated with significant body fat loss (ā€œOzempic faceā€).

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