Being a gym rat as far as doing moderate exercise regularly, I take regular measurements of my muscle size while maintaining a near-continuous BMI of 22.5 for the last ~ 3 years. Several of us on the forum are conducting a friendly competition to see if we can maintain weight and muscle mass.
Don’t laugh at the photo, after all, I am 83 years old and not a bodybuilder. (And yes, I am no@Bicept)
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Thank you for sharing. Impressive really. You are taking a good care of yourself and doing something very positive. When I exercise, I see a guys hanging out together at the park and smoking, they look aged and in poor shape…
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No one’s laughing, I promise 
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blsm
#24
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daily ~20% calorie reduction
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Its not you. I’ve set the software to automatically make the images full width of the message area, which is fine for most photos. But the phone screen shots are all vertical format, so I just adjust them to be more the actual size. No problem.
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I just must say - you are incredible! Love the photo, and also love your posts and intellect!
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I likely have a reasonable amount of time in recovery, and I have things I cycle in during recovery also. The 8 days works well for me. Other people like having a plan on a weekly basis. I like having a migrating schedule as I have things that I do on M/W/F, and things I do every 6 days, and things I’d not do while having MTORC1 inhibition.
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Thank you for starting this thread, it’s been very informative (and thanks to all the contributors). As of this post I’ve been on 10mg Rapamycin once weekly for almost 18 months - first in the PEARL clinical trial and then in the AgelessRx continuation program. I have noticed an apparent reduction in strength in my arms, but not much in my legs (I do a lot of squats). Quantitatively I’ve seen a small (1.5%) reduction in lean muscle mass (but also a significant reduction in visceral body fat), in 3 DXA scans over this 18 month period. I have found when I focused on regular arm exercises, there was a rebound in “felt” muscular strength. Recently on the advice of a sports medicine physician, I’ve raised my protein intake to about 120g per day, and started taking an EAA (essential amino acid) supplement at 1g per day. And I’m aiming to be even more diligent about regular full body exercises. My belief based on my experience is that there’s an adverse effect on muscular strength from Rapa if you don’t exercise, but you can overcome this with exercise. Your body responds when you ask it to!
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Interesting… I had been doing muscle resistance exercises a few years prior to starting on rapamycin. I have shredded fat in the muscles… but muscles and tendons retain strength… actually stronger. Increasing my lifts by 10 pounds every 3-4 months. Very strong right now.
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@tahoedenizen
Can you please share what percent reduction in visceral fat you’ve seen from the Dexa scans?
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A 30 percent reduction – actual numbers from 3.34 lb (uncomfortably high) to 2.34 lb visceral body fat, straight from the DexaFit app which saves the data from the scans.
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30 percent seems like quite a win. !
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Thank you for posting this as this is a major concern of mine. Can you provide some more detail on the protein per kg body weight you were eating before increasing to 120g, and can you provide some details about your weight training program during the period when you lost some arm strength and lean mass? If you wouldn’t mind, it would be particularly useful to know how many times per week you were lifting, how many reps and sets, what specific exercises (compound barbell lifts, machines, etc.) the level of perceived exertion (reps in reserve), and whether you were attempting a progressive overload program.
A 1.5% drop could just be measurement noise (Matt Kaberline’s recent podcast on DEXA discussed this), and it could also be water.
Are you still injecting 200mg testosterone per week though?
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Basically I’ve gone from about 0.7 to 1.4 g per kg of protein. My goal has been to get into the range of 1.2 - 2.0 g/kg recommended at https://onlinelibrary.wiley.com/doi/full/10.1111/nbu.12215. I do try to get some exercise every day, but I don’t track or keep records of reps, sets, machines, “perceived exertion”, etc. and no, I wasn’t attempting a “progressive overload program” (indeed I didn’t mention “weight training” or “lifting”, I do some but that’s not my primary form of exercise).
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Yes, going on 4.5 years of 200 mg…1 ml cypionate thigh injection weekly with 1 mg anastrozole.
I definitely think in combo with rapamycin it is a great way to keep muscle 
and reduce adipose tissue (body fat).
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First off I thought younger persons shouldn’t be taking Rapamycin for longevity. Older folks like myself are the ones who should be taking it and certainly not 16 mg a day or week as this guy suggest is happening. I joined the AgelessRX trial and I had to be within a certain age group. Im 76 and bike ride 25 miles two or three times a week depending on the weather. I take 15mg of the compounded form of Rapamycin which is equivalent to 6 MG of the normal brand. So younger people should avoid Rapamycin if their looking to build muscle. Remember Rapamycin works somewhat like fasting. Older fit folks that are not overweight tend to live longer.
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