#141

I’m with you there @Barnabas I’ve experienced the same side effects on Dutasteride 0.5 mg.

2 Likes
#142

Maybe take with tadalafil?
Again, I never had ED issues as a 33 years plus user nor my son a user of 3 years - he is 34 years old. For the majority - reseach says no issue. Not impossible. Worth trying.

Prevalence and Persistence

  • Low risk for most: The risk of developing ED with finasteride is generally low.
  • Possible persistence: While most instances of sexual dysfunction resolve after stopping finasteride, a small group of men report persistent symptoms that are difficult to treat.
3 Likes
#143

I don’t think it’s a matter of the drug being good or bad. Side effects happen to some people and not others, and if it works well for somebody without side effects that outweigh the benefits that’s great. I don’t think I need tadalafil. Maybe when I am older. For me getting my libido crushed was kind of a blessing more than a curse. I basically just stopped being an eternal eighth grader having a cartoon wolf moment once or twice a day.

3 Likes
#144

I’m still waiting for causal case reports where the patient isn’t suspected of being mentally ill :smiley:

2 Likes
#145

Dutasteride has given me endurance. Intimacy with my wife has gone from a sprint to a marathon.

I prefer it this way. :wink:

3 Likes
#146

Reduced Screening May Have Led to Rise in Advanced Prostate Cancer Diagnoses

Changes in screening recommendations over a decade ago may have inadvertently resulted in later diagnosis of the most common cancer in men, a new study has found.

Prostate cancer diagnoses have been rising in recent years, with a sharp increase in cases diagnosed at advanced stages, when it is harder to treat, according to a new report by the American Cancer Society. Many experts attributed the increase to a guideline change made over a decade ago that discouraged routine screening for the common cancer.

The new analysis also highlighted racial disparities that have persisted, despite overall declines in mortality. Black men develop prostate cancer at significantly higher rates than white men and die at twice the rate of white men. Native Americans die at higher rates although they have a lower incidence of the disease.

The report, published on Tuesday in the medical journal CA: A Cancer Journal for Clinicians, underscores the challenge of finding the right balance in cancer screening: Screen too much and you may end up causing harm by aggressively treating indolent disease that will never be life-threatening; screen too little and you may miss deadly disease.

In 2018, the task force said screening should be an individual decision for men 55 to 69 and should stop altogether at 70. The latter recommendation has given many doctors pause, now that men are living longer and could benefit from treatment even if they are in their 70s.

Many experts in the field say that reducing routine screening may have inadvertently led to a bump in severe disease.

Prostate cancer is the most common cancer affecting men, making up almost one-third of the cancers diagnosed. It is the second leading cause of cancer death for men after lung cancer. Some 313,780 cases of prostate cancer are expected to be diagnosed in the United States this year, and about 35,770 men will die of it.

全文：

https://www.nytimes.com/2025/09/02/science/prostate-cancer-rise-reduced-screening.html?unlocked_article_code=1.i08.kats.QvOyZizUKibf&smid=url-share

4 Likes
#147

I had a TURP 5 years ago for BPH and now my prostate has regrown to 52cc in size. My GP has prescribed Flomax 0.4mg and Finasteride 5mg. I have some concerns regarding side effects but I’m running out of non-invasive options.

2 Likes
#148

Have him prescribe tadalafil too. If you’re concern about ED. It a solid life extension medication and should put to bed (literally) any performance concerns.

4 Likes
#149

And maybe consider at least low-dose testosterone replacement/optimization which could help to offset potential finasteride side effects on mood, as long as the extra testosterone wouldn’t prevent your prostate from shrinking (if it did, it would be the T itself not DHT since you have that conversion blocked).

If you’re being managed by someone who knows what they’re doing, hopefully you could get it all dialed in and get the positives without the negatives.

3 Likes
#150

Find a good HOLEP surgeon in your area and fix the problem. You won’t regret it.

1 Like
#151
1 Like