Evidence of anti aging for human females

[Brigit_Pimm]

What is the evidence regarding anti aging effects of rapa in human females?

[约瑟夫]

FWIW I do not know of/am aware of any evidence of rapamycin showing/proving anti aging in humans.

We all are speculating.

Looking for the black cat in the dark room.

[Brigit_Pimm]

Well I am thinking of the anecdotal evidence. Eg people who say their grey hair is lessening, blood test biomarkers of aging and so on…given the differences in trial results on male/female mice and flies… does there seem to be any similar pattern forming in what people are reporting on their experiences…

[RapAdmin]

@Brigit_Pimm

What is the evidence regarding anti aging effects of rapa in human females?

The best clinical evidence are the phase 2 clinical trials by ResTOR Bio, worked in females and males in the phase 2 trial:

Rapamycin Clinical Studies in Healthy People (part 2)

[FluEld3] One of the big issues with understanding how rapamycin works in healthy people trying to prevent aging related disease and disfunction is that virtually all the clinical studies done with rapamycin over the past 20+ years, have almost all been done in very sick people. Specifically, people who have had organ transplants and are on a large number of drugs, or people who have cancer or heart disease and who again may be being treated with many other drugs simultaneously. In these applications the patients take rapamycin at high daily doses. So the side effects (and benefits) are going to be very different from what people will experience if they are healthy, taking low weekly doses of rapamycin as used in anti-aging. Rapalog Enhances Flue Shot Effectiveness by 20%, Minor Side Ef…

Other than that - in anecdotal form - see the benefits experienced by rapamycin - personal experiences

[David]

I shared this video recently. It may not be exactly what you are asking, but at least in the general direction. I believe that your question is at least being somewhat researched

Women's Health and Aging 03.28.2022