#101

Metabolic health is a common topic but the trends in terms of mechanisms show that its not what people might expect. For slowing aging in the strongest way actually a slower metabolism is ideal. “Metabolic health” in terms of a more active metabolism is often aimed for because theres a lot of overweight people. People think burning off calories is good so they can eat more, but what actually slows aging is the opposite.

The reason turtles and alligators have extremely slow aging is because their metabolism is slow and their body temp can be very low.

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#102

Regarding metabolic health, I was thinking more simply, as in no diabetes, low triglycerides, etc. — things to keep you from getting sick rather than for longevity. (Which, given the lack of conclusive research, I lumped in my “fourth” goal of diets).

#103

FWIW, I have always liked this way of thinking about aging and metabolism that is silly but instructive in my opinion. Imagine we have a fixed number of heart beats in our lifespan. It would be logical to think it best to not waste any heartbeats on exercise, but that is not right because RHR heart rate adapts over time in response to exercise. The average adult has a RHR of 60-100 bpm, but let’s call it 60. My RHR is 40 bpm because I have a strong heart in response to exercise. In simplistic terms my strong heart costs me an hour each day at 130-170 bpm (call it an extra 90 bmp x 60 min. = 5400 beats lost) but saves 20 bpm for 23 hours a day (20 bpm x 23 hours x 60 minutes /hour = 27,600 beats gained). The analogy can be extended to poor health plus carrying around extra weight plus being stressed a lot of the time…all of which cause a higher RHR, and a faster rate of using up heart beats. Now I just have to avoid getting run over while exercising.

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#104

Definitely a difference between men and women. My wife’s RHR is about 90, and a couple of the daughters are high too. Women usually outlive men.

But I love the idea of getting a certain number.

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#105

I reject the banana-broccoli shakes.

Most important thing for strength and muscle mass is simply exercising and having some protein powder. Isn’t harder than that.

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#106

Since this is pure fantasy, I’ll add one more.

No way do you get a certain number. Some people are pumping excess fat and sugar all the time. Some have high microbial burden and LPS, and insulin is high because it’s stopped working. So this is a case of too many nutrients.

Also there are cases of not enough nutrients to feed the heart so that it keeps working. Take your pick of the vitamins and Minerals.

#107

My average RHR for the year is 44. When I sleep it falls to 38-39. The highest RHR for the week was 48. My cardiologist is happy about it.

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#108

I completely disagree with this statement. It is utterly blind, it is the prevention of diseases or delaying them that matters. And most of this is done by lifestyle. Really simple interventions make up probably most of our healthspan. Exercise, not smoking, eating and drinking alcohol in moderation. With eating probably even restriction does not hurt probably. Really simple.
Maybe the last 10-20% are drugs, but they can really do so much in offsetting bad lifestyle choices.
Drugs are developed for sick people to alleviate symptoms as health is conceptualized as an absence of symptoms. They are rarely curative.

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#109

I said future drug development. Of course you shouldn’t smoke or excessively drink alcohol, that would reduce your healthspan for little to no positive valence, in my opinion. However food can be unhealthy, provide positive valence at the same time not have much of an effect on healthspan if you do other things right.

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#110

@LaraPo very good. What do you do to maintain a low RHR?

#111

I guess it comes naturally. All my life I was in all kinds of sports, from gymnastics to scuba and downhill skiing, then into dancing. It trained my heart. Trying to stay active every day. Never smoked and don’t consume alcohol.

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#112

@LaraPo Very interesting. Maybe I’m doing more than I need to do. But I enjoy my workouts. It’s a hobby.

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#113

Given the discussion about fitness and rhr perhaps this should go here. I don’t think it is surprising, but I have not seen it before.

https://www.mayoclinicproceedings.org/article/S0025-6196(13)00830-6/fulltext

Protective Role of Resting Heart Rate on All-Cause and Cardiovascular Disease Mortality

Highest cardiorespiratory fitness with lower mortality was found in individuals with an RHR of less than 60 beats/min. Similarly, patients with a higher RHR (≥80 beats/min) were at greater risk for CVD and all-cause mortality compared with an RHR of less than 60 beats/min. This analysis was followed by stratification of the data by hypertension, where hypertensive individuals with high RHRs (≥80 beats/min) were found to be at greater risk for CVD and all-cause mortality compared with those with hypertension and lower RHRs (<60 beats/min). In addition, unfit individuals with high RHRs had the greatest risk of CVD and all-cause mortality. The unfit with low RHR group had a similar risk for CVD and all-cause mortality as the fit with high RHR group.

Perhaps the interesting newsy bit from this (the paper was 2013) is this:

The unfit with low RHR group had a similar risk for CVD and all-cause mortality as the fit with high RHR group.

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#114

@John_Hemming Bradycardia is what I was always accused of having when my HR is first taken at a Dr office. Apparently it’s a bad thing. The category of unfit and low RHR must include this condition.

#115

FRESH FOOD AND FOOD POISONING

So after some days of going back to junk food/processed food I probably got some food poisoning.
I realize that it’s not good, especially depending on chronological age/biological age, also if mTOR is suppressed or not. It’s another factor of certainty that should be considered when it comes to diet and healthspan IMO.

So I’m going to try more fresh food and avoiding to make leftovers. What type of fruit/vegetables should be avoided, etc? Dried food that is then cooked should be good right? What about canned food?

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From CDC

#116

I think you need to give more details as the food you consider to be junk or processed.

Today I started with beans on toast with Branstons Pickle. Now the beans were Heinz from a can.

However, I think they are a reasonably good food. Yesterday I mainly fasted although I had some cheese wrapped in beef at about 7am. (then tea, water, tisane).

I must admit that at lunch time I fell off the wagon I had some chia seeds and a salad then went to the pub and had a couple of pints of bitter. I then took some beer home. I am now having an apple and will move on to cider soon.

#117

For this “factor”, I don’t really mind if it’s processed, I don’t think beans or peaches in a can, or anything else in a can should be risky for food poisoning. As it should be pasteurized and the best-before is long. Focus on cooked food and no leftovers? Of course certain fruit that is washed doesn’t seem risky at all, never heard there being a problem with that. Beer and cider is also probably safe but unhealthy in large amounts for other reasons. Tea also safe. Dried nuts/fruit/seeds as well?

Bread might be good to buy as soon as it’s delivered to the store, then freezing it immediately?

This was evidently a much larger problem in the past and probably a massive killer before antibiotics and sanitation, but still might be worthwhile to consider as a factor with possible resistant bacteria in future/and annoying to get food poisoning. Probably also why beer/tea/coffee etc became so popular as a drink.

#118

Beer was popular as a drink because the alcohol killed a number of bacteria so it was less likely to poison people than water.

Two different views on this:

http://che.umbc.edu/londontown/cookbook/drinks.html

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#119

Try steeping rosemary in hot water and then making lemonade out of it. Fantastic. A Persian thing.

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#120

Thank you. I will make rosemary tea, cool it, mix in some lemon, then sweeten with glycine.

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