Yes I’m amazed anyone would recommend aspartame.

There’s so much evidence now of how bad it is for the gut microbiome, glucose tolerance and adiposity.
1 study found it reduced the number of phyla in the gut from 24 to 7 in just 4 days!

Effect of Non-Nutritive Sweeteners on the Gut Microbiota.

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hello, I have read your posts about neprinol.
will 3-4 capsules a day do the job or is necessary to take 3x3 ?
49 ys, some spots on both carotids, smoker, 67% obstruction of LAD
no simptoms, treadmil test ok
also pomegranate juice 100 ml a day, vit k
thank you

Did 3x3 fit about six months then tapered. Now, twenty years later, I buy a 150 cap bottle once a year and just take random amounts as convenient (sometime I gotta eat in the morning—remember to take in empty stomach!) until I finish bottle. Ca scan was 9, carotids still clear—so I’m not stopping this routine!

I know I am late in responding. It depends on what you consider a healthful diet. Healthy eating has become a social normative belief – i.e., people get a feeling of social approval (like when people believe they are smarter or better looking than average). But if every diet can be ranked on a 100-point scale, clearly not all healthful diets are equal. And yet most people overestimate the healthfulness of their diets.

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With all the different diets, and I studied too many to list, the ones that actually work great for some people all have one thing in common. They work if it makes people eat significantly less.

Those who think they can just go Mediterranean or whatever and then splurge, well, it is like obese adding a vitamin smoothy to donuts thinking that now they made all more healthy rather than even worse.

So, your 100 point scale would actually be dependent on that much more than on the type (e.g. low carb versus low fat) of diet.

And reading up on that, let me guess, you find that winter fat evolved for a reason. This is why these gym rats that desire zero fat at all cost are so silly. Animals have some fat for good reasons.

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I agree generally. But 99% of people either cannot eat less (and “less” means not 20% less than an over-weight diet but 20% less than a normal diet) or are unaware of calorie restriction.

And by “diet” I do not mean a popular (and thus easy) diet like the Mediterranean. I mean an almost 100% diverse, whole plant, high polyphenol diet consisting of all 8 kinds of plant food: fruit, veggies, whole grains, nuts and seeds, beans and legumes, mushrooms (technically not a plant), seaweed, and herbs and spices.

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Oh, I just thought it was interesting. I personally do best on a moderate fat intake right now but it I’ve been keto in the past. Eating a whole/minimally processed omnivore diet provides me with enough naturally occurring fats that I don’t feel the need to add extra. I will most definitely never argue with, debate or judge anyone over diet and I respect everyone’s personal choices on how they eat.:blush:

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@blsm I was refering to the body fat that your previous comment was also about. Body fat is put on before winter, regardless of any fat in the diet. Your body makes your body fat. It does not put on the fat you eat. If you eat lots of tallow, your body fat is not tallow.

Well, you wrote about ranking all diets, and there are many different diets. The reason is psychological. Most people do know well that eating less is healthy, not eating yet more of supposedly healthy food. But human rationality socially evolved to rationalize emotional decisions. So, people very efficiently circumvent the knowledge they actually have and find ever new ways to not do what they should do, such as trying a new diet.

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Oh okay, sorry I misunderstood what the comment was about.

I seriously doubt that. My body fat does not change seasonally. I wish it did. With Rapamycin, it looks impossible to accumulate any fat and/or gain weight.

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we were talking about evolution

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https://www.nature.com/articles/s43856-025-00754-5#Abs2

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so if I take 3x3 neprinol a day for say 9 months will I get rid of general atheroma?

Eat plants say “researchers” from the “College of Economics and Management, China Agricultural University” after performing some bogus statistical analysis on a cohort of people with an average BMI of 27.2.

Scientist previously at Apple goes through a presentation he had at a low carb conference, the complete opposite of his bias, regarding what big data tells us is the best diet.

It’s great.

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Cool that he doesn’t consider people who have “different facts” to be the enemy. Or anyway if he does, he does a good job of hiding it.

More power to him and I hope it works for him.

A longevity scientist who says he’s reversed his age by 15 years shares the diet he follows — and 3 foods he avoids

Swears by: eating a Mediterranean-style diet

Verdin said that there’s strong evidence to suggest eating a good balance of complex carbohydrates — such as sweet potatoes — fats, and proteins is essential for health.

He follows the principles of the Mediterranean diet, which is based on the traditional eating habits of people in countries such as Greece, Italy, and Turkey, and has been ranked the healthiest way to eat by the US News & World Report for eight years running.

“When you look at populations that are on this type of diet, they really are the healthy ones,” Verdin said.

The eating plan emphasizes fruits and vegetables, whole grains, legumes, nuts and seeds, and lean sources of protein such as fish.

Read the full story: A longevity scientist who says he’s reversed his age by 15 years shares the diet he follows — and 3 foods he avoids

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